| 1 | Roy Halladay | 19 | 6 | 0 | 32 | 32 | 233.2 | 8.47 | 1.35 | 0.39 | .298 | 78.1% | 50.9% | 5.1% | 92.3 | 2.35 | | 2.20 | 2.71 | 8.7 |
| 2 | Cliff Lee | 17 | 8 | 0 | 32 | 32 | 232.2 | 9.21 | 1.62 | 0.70 | .291 | 81.4% | 46.3% | 9.0% | 92.1 | 2.40 | | 2.60 | 2.68 | 7.1 |
| 3 | Cole Hamels | 14 | 9 | 0 | 32 | 31 | 216.0 | 8.08 | 1.83 | 0.79 | .255 | 78.4% | 52.3% | 9.9% | 92.5 | 2.79 | | 3.05 | 3.02 | 5.1 |
| 4 | Roy Oswalt | 9 | 10 | 0 | 23 | 23 | 139.0 | 6.02 | 2.14 | 0.65 | .316 | 74.0% | 45.1% | 6.3% | 92.4 | 3.69 | | 3.44 | 3.95 | 2.8 |
| 5 | Vance Worley | 11 | 3 | 0 | 25 | 21 | 131.2 | 8.13 | 3.14 | 0.68 | .283 | 78.1% | 39.3% | 7.2% | 91.1 | 3.01 | | 3.32 | 3.66 | 2.3 |
| 6 | Ryan Madson | 4 | 2 | 32 | 62 | 0 | 60.2 | 9.20 | 2.37 | 0.30 | .315 | 80.6% | 48.8% | 3.7% | 95.0 | 2.37 | | 2.25 | 2.94 | 1.8 |
| 7 | Antonio Bastardo | 6 | 1 | 8 | 64 | 0 | 58.0 | 10.86 | 4.03 | 0.93 | .179 | 81.1% | 25.4% | 8.1% | 93.4 | 2.64 | | 3.30 | 3.56 | 1.0 |
| 8 | Joe Blanton | 1 | 2 | 0 | 11 | 8 | 41.1 | 7.62 | 1.96 | 1.09 | .362 | 70.9% | 55.0% | 13.9% | 90.2 | 5.01 | | 3.63 | 3.15 | 0.6 |
| 9 | Brad Lidge | 0 | 2 | 1 | 25 | 0 | 19.1 | 10.71 | 6.05 | 0.00 | .327 | 90.0% | 57.4% | 0.0% | 89.6 | 1.40 | | 2.82 | 3.40 | 0.3 |
| 10 | Michael Stutes | 6 | 2 | 0 | 57 | 0 | 62.0 | 8.42 | 4.06 | 1.02 | .256 | 78.0% | 32.9% | 8.8% | 93.8 | 3.63 | | 4.07 | 4.23 | 0.3 |
| 11 | Jose Contreras | 0 | 0 | 5 | 17 | 0 | 14.0 | 8.36 | 5.14 | 0.00 | .289 | 70.0% | 45.9% | 0.0% | 93.8 | 3.86 | | 3.10 | 3.99 | 0.2 |
| 12 | Kyle Kendrick | 8 | 6 | 0 | 34 | 15 | 114.2 | 4.63 | 2.35 | 1.10 | .261 | 76.1% | 45.3% | 10.5% | 82.6 | 3.22 | | 4.55 | 4.42 | 0.2 |
| 13 | Juan Perez | 1 | 0 | 0 | 8 | 0 | 5.0 | 14.40 | 9.00 | 0.00 | .125 | 66.7% | 37.5% | 0.0% | 94.7 | 3.60 | | 2.83 | 3.83 | 0.1 |
| 14 | Joe Savery | 0 | 0 | 0 | 4 | 0 | 2.2 | 6.75 | 0.00 | 0.00 | .143 | 100.0% | 50.0% | 0.0% | 91.5 | 0.00 | | 1.53 | 2.47 | 0.1 |
| 15 | J.C. Romero | 0 | 0 | 0 | 24 | 0 | 16.1 | 5.51 | 6.61 | 0.00 | .308 | 75.9% | 52.9% | 0.0% | 89.9 | 3.86 | | 4.19 | 5.65 | 0.0 |
| 16 | Scott Mathieson | 0 | 0 | 0 | 4 | 0 | 5.0 | 9.00 | 5.40 | 0.00 | .500 | 100.0% | 35.3% | 0.0% | 93.9 | 0.00 | | 4.03 | 5.53 | 0.0 |
| 17 | Justin De Fratus | 1 | 0 | 0 | 5 | 0 | 4.0 | 6.75 | 6.75 | 0.00 | .100 | 60.0% | 44.4% | 0.0% | 92.9 | 2.25 | | 4.53 | 5.78 | 0.0 |
| 18 | Wilson Valdez | 1 | 0 | 0 | 1 | 0 | 1.0 | 0.00 | 0.00 | 0.00 | .000 | 100.0% | 0.0% | 0.0% | 88.1 | 0.00 | | 6.03 | 9.79 | 0.0 |
| 19 | Michael Schwimer | 1 | 1 | 0 | 12 | 0 | 14.1 | 10.05 | 4.40 | 1.26 | .342 | 74.3% | 19.4% | 12.5% | 92.3 | 5.02 | | 4.28 | 3.87 | -0.1 |
| 20 | Andrew Carpenter | 0 | 0 | 0 | 6 | 0 | 9.1 | 9.64 | 3.86 | 1.93 | .393 | 63.4% | 31.0% | 16.7% | | 7.71 | | 4.95 | 3.78 | -0.1 |
| 21 | Mike Zagurski | 0 | 0 | 0 | 4 | 0 | 3.1 | 10.80 | 8.10 | 2.70 | .333 | 89.3% | 50.0% | 20.0% | 92.5 | 5.40 | | 7.23 | 5.21 | -0.1 |
| 22 | Danys Baez | 2 | 4 | 0 | 29 | 0 | 36.0 | 4.50 | 3.25 | 1.25 | .306 | 59.6% | 52.7% | 13.5% | 92.9 | 6.25 | | 5.16 | 4.65 | -0.3 |
| 23 | David Herndon | 1 | 4 | 1 | 45 | 0 | 57.0 | 6.16 | 3.79 | 1.42 | .266 | 80.1% | 54.4% | 18.0% | 93.3 | 3.32 | | 5.08 | 4.13 | -0.6 |