| 1 | Taylor Hill | 0 | 1 | 0 | 3 | 1 | 9.0 | 5.00 | 3.00 | 0.00 | .457 | 57.1% | 52.9% | 0.0% | 91.0 | 9.00 | | 3.69 | 4.65 | 0.1 |
| 2 | Xavier Cedeno | 0 | 0 | 0 | 9 | 0 | 7.0 | 6.43 | 0.00 | 1.29 | .375 | 69.8% | 37.5% | 14.3% | 92.3 | 3.86 | | 3.56 | 2.94 | 0.0 |
| 3 | Blake Treinen | 2 | 3 | 0 | 15 | 7 | 50.2 | 5.33 | 2.31 | 0.18 | .333 | 77.9% | 59.3% | 3.1% | 95.8 | 2.49 | | 3.09 | 3.62 | 0.7 |
| 4 | Taylor Jordan | 0 | 3 | 0 | 5 | 5 | 25.2 | 5.96 | 2.81 | 1.05 | .330 | 60.3% | 53.2% | 11.1% | 90.5 | 5.61 | | 4.50 | 4.28 | 0.1 |
| 5 | Craig Stammen | 4 | 5 | 0 | 49 | 0 | 72.2 | 6.94 | 1.73 | 0.62 | .323 | 69.3% | 48.0% | 7.7% | 92.5 | 3.84 | | 3.19 | 3.40 | 0.6 |
| 6 | Stephen Strasburg | 14 | 11 | 0 | 34 | 34 | 215.0 | 10.13 | 1.80 | 0.96 | .315 | 74.8% | 45.9% | 13.1% | 95.6 | 3.14 | | 2.94 | 2.56 | 4.5 |
| 7 | Aaron Barrett | 3 | 0 | 0 | 50 | 0 | 40.2 | 10.84 | 4.43 | 0.22 | .311 | 70.3% | 46.1% | 3.4% | 94.4 | 2.66 | | 2.59 | 3.15 | 0.7 |
| 8 | Ross Detwiler | 2 | 3 | 1 | 47 | 0 | 63.0 | 5.57 | 3.00 | 0.71 | .309 | 69.0% | 46.3% | 7.4% | 94.3 | 4.00 | | 4.16 | 4.47 | -0.1 |
| 9 | Jerry Blevins | 2 | 3 | 0 | 64 | 0 | 57.1 | 10.36 | 3.61 | 0.47 | .306 | 60.5% | 38.8% | 5.6% | 91.8 | 4.87 | | 2.77 | 3.25 | 0.8 |
| 10 | Jordan Zimmermann | 14 | 5 | 0 | 32 | 32 | 199.2 | 8.20 | 1.31 | 0.59 | .302 | 75.8% | 40.1% | 6.4% | 94.5 | 2.66 | | 2.68 | 3.10 | 5.4 |
| 11 | Matt Thornton | 1 | 0 | 0 | 18 | 0 | 11.1 | 6.35 | 1.59 | 0.00 | .294 | 100.0% | 55.9% | 0.0% | 96.5 | 0.00 | | 2.51 | 3.71 | 0.2 |
| 12 | Gio Gonzalez | 10 | 10 | 0 | 27 | 27 | 158.2 | 9.19 | 3.18 | 0.57 | .294 | 70.9% | 44.8% | 6.6% | 93.0 | 3.57 | | 3.03 | 3.39 | 3.3 |
| 13 | Rafael Soriano | 4 | 1 | 32 | 64 | 0 | 62.0 | 8.56 | 2.76 | 0.58 | .280 | 73.8% | 31.6% | 4.8% | 91.8 | 3.19 | | 3.08 | 3.92 | 0.8 |
| 14 | Tanner Roark | 15 | 10 | 0 | 31 | 31 | 198.2 | 6.25 | 1.77 | 0.72 | .270 | 79.3% | 41.4% | 7.0% | 91.8 | 2.85 | | 3.47 | 3.84 | 3.3 |
| 15 | Ryan Mattheus | 0 | 0 | 0 | 7 | 0 | 8.2 | 4.15 | 4.15 | 0.00 | .269 | 91.7% | 50.0% | 0.0% | 93.2 | 1.04 | | 3.94 | 4.94 | 0.0 |
| 16 | Doug Fister | 16 | 6 | 0 | 25 | 25 | 164.0 | 5.38 | 1.32 | 0.99 | .262 | 83.1% | 48.9% | 10.1% | 88.5 | 2.41 | | 3.93 | 3.85 | 1.5 |
| 17 | Drew Storen | 2 | 1 | 11 | 65 | 0 | 56.1 | 7.35 | 1.76 | 0.32 | .259 | 90.6% | 52.5% | 3.8% | 94.3 | 1.12 | | 2.71 | 3.39 | 1.0 |
| 18 | Tyler Clippard | 7 | 4 | 1 | 75 | 0 | 70.1 | 10.49 | 2.94 | 0.64 | .251 | 76.6% | 36.9% | 6.0% | 92.5 | 2.18 | | 2.75 | 3.28 | 1.5 |