| 1 | Hector Santiago | - - - | 13 | 10 | 0 | 33 | 33 | 182.0 | 7.12 | 3.91 | 1.63 | .260 | 74.0% | 34.1% | 12.0% | 4.70 | 5.31 | 5.46 | 0.8 | 50.0% |
| 2 | Drew Smyly | TBR | 7 | 12 | 0 | 30 | 30 | 175.1 | 8.57 | 2.52 | 1.64 | .291 | 67.7% | 31.3% | 12.7% | 4.88 | 4.49 | 4.51 | 1.8 | 49.3% |
| 3 | Marco Estrada | TOR | 9 | 9 | 0 | 29 | 29 | 176.0 | 8.44 | 3.32 | 1.18 | .234 | 75.8% | 33.5% | 9.9% | 3.48 | 4.15 | 4.64 | 2.7 | 48.2% |
| 4 | Jered Weaver | LAA | 12 | 12 | 0 | 31 | 31 | 178.0 | 5.21 | 2.58 | 1.87 | .301 | 74.5% | 28.8% | 12.7% | 5.06 | 5.62 | 5.64 | 0.1 | 48.2% |
| 5 | Dan Straily | CIN | 14 | 8 | 0 | 34 | 31 | 191.1 | 7.62 | 3.43 | 1.46 | .239 | 81.2% | 32.0% | 12.0% | 3.76 | 4.88 | 5.02 | 1.2 | 48.0% |
| 6 | Max Scherzer | WSN | 20 | 7 | 0 | 34 | 34 | 228.1 | 11.19 | 2.21 | 1.22 | .255 | 81.7% | 33.0% | 11.9% | 2.96 | 3.24 | 3.37 | 5.6 | 47.9% |
| 7 | A.J. Griffin | TEX | 7 | 4 | 0 | 23 | 23 | 119.0 | 8.09 | 3.48 | 2.12 | .274 | 77.8% | 29.1% | 16.9% | 5.07 | 5.74 | 5.01 | 0.2 | 47.8% |
| 8 | Justin Verlander | DET | 16 | 9 | 0 | 34 | 34 | 227.2 | 10.04 | 2.25 | 1.19 | .255 | 79.9% | 33.7% | 10.9% | 3.04 | 3.48 | 3.78 | 5.4 | 47.7% |
| 9 | Colby Lewis | TEX | 6 | 5 | 0 | 19 | 19 | 116.1 | 5.65 | 2.17 | 1.47 | .241 | 75.4% | 34.1% | 11.1% | 3.71 | 4.81 | 5.14 | 1.1 | 47.4% |
| 10 | Ian Kennedy | KCR | 11 | 11 | 0 | 33 | 33 | 195.2 | 8.46 | 3.04 | 1.52 | .268 | 83.1% | 33.2% | 12.8% | 3.68 | 4.67 | 4.67 | 2.0 | 47.3% |
| 11 | Eduardo Rodriguez | BOS | 3 | 7 | 0 | 20 | 20 | 107.0 | 8.41 | 3.36 | 1.35 | .278 | 70.2% | 31.6% | 11.1% | 4.71 | 4.43 | 4.72 | 1.2 | 46.0% |
| 12 | Jake Peavy | SFG | 5 | 9 | 0 | 31 | 21 | 118.2 | 7.74 | 2.73 | 1.37 | .320 | 65.4% | 36.4% | 10.9% | 5.54 | 4.36 | 4.70 | 0.7 | 44.5% |
| 13 | Jake Odorizzi | TBR | 10 | 6 | 0 | 33 | 33 | 187.2 | 7.96 | 2.59 | 1.39 | .271 | 79.0% | 36.6% | 12.0% | 3.69 | 4.31 | 4.44 | 1.8 | 44.4% |
| 14 | Clay Buchholz | BOS | 8 | 10 | 0 | 37 | 21 | 139.1 | 6.01 | 3.55 | 1.36 | .263 | 68.5% | 41.2% | 11.4% | 4.78 | 5.06 | 5.32 | 0.4 | 43.0% |
| 15 | Danny Duffy | KCR | 12 | 3 | 0 | 42 | 26 | 179.2 | 9.42 | 2.10 | 1.35 | .291 | 80.9% | 36.4% | 13.0% | 3.51 | 3.83 | 3.79 | 2.9 | 42.8% |
| 16 | Dylan Bundy | BAL | 10 | 6 | 0 | 36 | 14 | 109.2 | 8.53 | 3.45 | 1.48 | .299 | 79.7% | 35.9% | 13.3% | 4.02 | 4.70 | 4.61 | 1.0 | 42.2% |
| 17 | Matt Moore | - - - | 13 | 12 | 0 | 33 | 33 | 198.1 | 8.08 | 3.27 | 1.13 | .285 | 74.4% | 38.2% | 10.4% | 4.08 | 4.17 | 4.56 | 2.0 | 42.1% |
| 18 | Julio Teheran | ATL | 7 | 10 | 0 | 30 | 30 | 188.0 | 7.99 | 1.96 | 1.05 | .260 | 77.8% | 39.1% | 10.0% | 3.21 | 3.69 | 4.13 | 3.0 | 41.9% |
| 19 | Madison Bumgarner | SFG | 15 | 9 | 0 | 34 | 34 | 226.2 | 9.97 | 2.14 | 1.03 | .265 | 79.1% | 39.6% | 10.7% | 2.74 | 3.24 | 3.54 | 4.3 | 41.5% |
| 20 | Anibal Sanchez | DET | 7 | 13 | 0 | 35 | 26 | 153.1 | 7.92 | 3.11 | 1.76 | .317 | 64.7% | 39.6% | 15.5% | 5.87 | 5.06 | 4.62 | 1.0 | 41.3% |
| 21 | Vince Velasquez | PHI | 8 | 6 | 0 | 24 | 24 | 131.0 | 10.44 | 3.09 | 1.44 | .325 | 76.2% | 34.8% | 14.9% | 4.12 | 3.96 | 3.67 | 2.3 | 41.2% |
| 22 | Chase Anderson | MIL | 9 | 11 | 0 | 31 | 30 | 151.2 | 7.12 | 3.15 | 1.66 | .287 | 74.7% | 36.1% | 14.9% | 4.39 | 5.09 | 4.76 | 0.4 | 41.1% |
| 23 | Adam Conley | MIA | 8 | 6 | 0 | 25 | 25 | 133.1 | 8.37 | 4.18 | 0.88 | .299 | 77.3% | 38.2% | 8.5% | 3.85 | 4.20 | 4.84 | 1.6 | 41.1% |
| 24 | Chris Devenski | HOU | 4 | 4 | 1 | 48 | 5 | 108.1 | 8.64 | 1.66 | 0.33 | .271 | 78.8% | 33.5% | 3.5% | 2.16 | 2.34 | 3.60 | 2.7 | 40.6% |
| 25 | Yu Darvish | TEX | 7 | 5 | 0 | 17 | 17 | 100.1 | 11.84 | 2.78 | 1.08 | .290 | 73.3% | 40.4% | 12.0% | 3.41 | 3.09 | 3.19 | 2.8 | 40.0% |
| 26 | Derek Holland | TEX | 7 | 9 | 0 | 22 | 20 | 107.1 | 5.62 | 2.93 | 1.26 | .295 | 68.9% | 38.3% | 10.6% | 4.95 | 4.75 | 5.14 | 1.1 | 40.0% |
| 27 | Brandon Finnegan | CIN | 10 | 11 | 0 | 31 | 31 | 172.0 | 7.59 | 4.40 | 1.52 | .256 | 77.0% | 38.1% | 14.9% | 3.98 | 5.19 | 4.87 | 0.7 | 39.4% |
| 28 | Jerad Eickhoff | PHI | 11 | 14 | 0 | 33 | 33 | 197.1 | 7.62 | 1.92 | 1.37 | .278 | 76.4% | 40.7% | 13.1% | 3.65 | 4.19 | 4.15 | 3.0 | 39.3% |
| 29 | Stephen Strasburg | WSN | 15 | 4 | 0 | 24 | 24 | 147.2 | 11.15 | 2.68 | 0.91 | .294 | 73.6% | 39.5% | 10.6% | 3.60 | 2.92 | 3.20 | 4.0 | 39.2% |
| 30 | Jordan Zimmermann | DET | 9 | 7 | 0 | 19 | 18 | 105.1 | 5.64 | 2.22 | 1.20 | .304 | 65.7% | 43.1% | 10.3% | 4.87 | 4.42 | 4.84 | 1.4 | 38.9% |