| 1 | Matt Cain | SFG | .268 | 0.88 | 19.2% | 37.8% | 43.0% | 11.8% | 6.7% | 571 | 3.95 | 7286 | 13367 | 20653 | 35.8% | 37.0% | 27.1% | 18.1% | 54.2% | 27.8% |
| 2 | Clayton Kershaw | LAD | .275 | 1.15 | 18.8% | 43.4% | 37.8% | 12.6% | 6.8% | 444 | 4.23 | 5603 | 9614 | 15217 | 38.9% | 32.9% | 28.2% | 22.2% | 54.5% | 23.2% |
| 3 | Josh Johnson | FLA | .300 | 1.51 | 20.6% | 47.7% | 31.7% | 10.3% | 6.8% | 385 | 4.64 | 4407 | 7682 | 12089 | 37.8% | 34.1% | 28.1% | 17.3% | 57.2% | 25.5% |
| 4 | Chris Carpenter | STL | .289 | 1.68 | 19.7% | 50.4% | 29.9% | 8.1% | 7.3% | 335 | 4.29 | 3691 | 6709 | 10400 | 40.5% | 35.5% | 24.0% | 19.5% | 55.7% | 24.8% |
| 5 | Justin Verlander | DET | .281 | 0.99 | 19.5% | 40.1% | 40.5% | 11.2% | 7.6% | 795 | 5.28 | 7810 | 14464 | 22274 | 37.1% | 33.2% | 29.7% | 19.5% | 54.6% | 25.9% |
| 6 | Chad Billingsley | LAD | .302 | 1.36 | 19.8% | 46.2% | 34.0% | 7.5% | 7.6% | 582 | 4.88 | 6735 | 11093 | 17828 | 38.1% | 36.3% | 25.6% | 17.8% | 55.2% | 27.0% |
| 7 | Mike Pelfrey | NYM | .306 | 1.56 | 20.3% | 48.6% | 31.1% | 9.0% | 7.7% | 428 | 4.40 | 5672 | 9022 | 14694 | 34.5% | 37.6% | 28.0% | 19.3% | 54.1% | 26.6% |
| 8 | Jered Weaver | LAA | .275 | 0.72 | 18.8% | 33.9% | 47.3% | 12.8% | 7.7% | 682 | 5.13 | 7013 | 12481 | 19494 | 41.9% | 33.6% | 24.5% | 22.1% | 51.7% | 26.2% |
| 9 | Jair Jurrjens | - - - | .286 | 1.22 | 19.9% | 44.0% | 36.1% | 8.7% | 7.7% | 402 | 4.82 | 4279 | 7524 | 11803 | 34.3% | 39.0% | 26.7% | 17.6% | 54.7% | 27.6% |
| 10 | Adam Wainwright | STL | .294 | 1.60 | 19.2% | 49.7% | 31.1% | 10.2% | 7.9% | 612 | 5.53 | 5488 | 9699 | 15187 | 40.1% | 35.5% | 24.4% | 17.1% | 57.1% | 25.9% |
| 11 | Cliff Lee | - - - | .301 | 1.15 | 19.3% | 43.2% | 37.5% | 10.8% | 8.0% | 633 | 4.71 | 5530 | 12421 | 17951 | 36.4% | 35.0% | 28.7% | 18.7% | 54.1% | 27.3% |
| 12 | Doug Fister | - - - | .287 | 1.48 | 20.2% | 47.6% | 32.2% | 9.4% | 8.0% | 273 | 4.03 | 3210 | 6164 | 9374 | 41.6% | 35.1% | 23.3% | 20.2% | 53.6% | 26.2% |
| 13 | Zack Greinke | - - - | .308 | 1.20 | 20.1% | 43.5% | 36.4% | 8.5% | 8.3% | 649 | 5.05 | 6788 | 11668 | 18456 | 38.8% | 33.3% | 27.9% | 17.6% | 53.4% | 28.9% |
| 14 | Carlos Zambrano | - - - | .285 | 1.30 | 19.0% | 45.8% | 35.2% | 12.3% | 8.4% | 563 | 5.16 | 6538 | 10057 | 16595 | 36.7% | 35.5% | 27.8% | 21.3% | 54.7% | 24.0% |
| 15 | Kyle Lohse | - - - | .291 | 1.15 | 21.8% | 41.8% | 36.4% | 10.2% | 8.5% | 540 | 4.85 | 5618 | 10112 | 15730 | 40.5% | 34.0% | 25.5% | 18.3% | 52.2% | 29.6% |
| 16 | Tim Lincecum | SFG | .295 | 1.41 | 19.9% | 46.9% | 33.3% | 7.5% | 8.5% | 593 | 4.40 | 7373 | 12477 | 19850 | 39.2% | 35.5% | 25.3% | 17.4% | 55.8% | 26.8% |
| 17 | C.J. Wilson | - - - | .282 | 1.62 | 19.0% | 50.0% | 30.9% | 6.4% | 8.5% | 419 | 4.61 | 5431 | 8392 | 13823 | 38.1% | 36.6% | 25.3% | 19.1% | 54.4% | 26.6% |
| 18 | Jake Peavy | - - - | .281 | 1.00 | 19.4% | 40.3% | 40.4% | 12.1% | 8.5% | 507 | 4.87 | 5195 | 9903 | 15098 | 38.3% | 34.2% | 27.5% | 18.9% | 54.3% | 26.8% |
| 19 | Ubaldo Jimenez | - - - | .291 | 1.47 | 19.0% | 48.2% | 32.7% | 9.3% | 8.6% | 590 | 4.89 | 7251 | 10995 | 18246 | 36.6% | 36.4% | 27.0% | 18.4% | 55.5% | 26.2% |
| 20 | Tim Wakefield | BOS | .274 | 0.81 | 16.8% | 37.2% | 46.0% | 12.9% | 8.6% | 525 | 5.95 | 4247 | 8015 | 12262 | 49.4% | 31.5% | 19.1% | 20.2% | 51.8% | 28.0% |
| 21 | CC Sabathia | - - - | .296 | 1.39 | 19.8% | 46.7% | 33.5% | 9.2% | 8.7% | 882 | 5.67 | 7290 | 13911 | 21201 | 39.7% | 33.5% | 26.8% | 20.7% | 53.6% | 25.7% |
| 22 | Daisuke Matsuzaka | BOS | .294 | 0.82 | 19.0% | 36.5% | 44.5% | 10.6% | 8.7% | 418 | 5.63 | 4372 | 7237 | 11609 | 38.2% | 35.3% | 26.5% | 18.5% | 49.8% | 31.7% |
| 23 | Barry Zito | SFG | .279 | 0.93 | 20.8% | 38.1% | 41.1% | 10.6% | 8.7% | 486 | 4.35 | 6479 | 10527 | 17006 | 41.1% | 34.3% | 24.6% | 20.1% | 53.3% | 26.6% |
| 24 | Anibal Sanchez | - - - | .309 | 1.25 | 19.9% | 44.5% | 35.6% | 10.8% | 8.8% | 339 | 4.04 | 4488 | 7959 | 12447 | 40.2% | 33.8% | 26.0% | 19.7% | 52.4% | 27.9% |
| 25 | Scott Baker | MIN | .300 | 0.76 | 20.9% | 34.1% | 45.0% | 12.9% | 9.0% | 483 | 5.29 | 4076 | 8778 | 12854 | 37.0% | 33.2% | 29.8% | 19.3% | 51.5% | 29.2% |
| 26 | Andy Pettitte | NYY | .310 | 1.43 | 19.0% | 47.7% | 33.4% | 9.8% | 9.1% | 522 | 5.74 | 4847 | 8240 | 13087 | 41.5% | 32.6% | 25.9% | 18.4% | 54.2% | 27.4% |
| 27 | Brandon Morrow | - - - | .291 | 0.88 | 19.4% | 37.8% | 42.8% | 9.7% | 9.1% | 350 | 4.86 | 4188 | 6980 | 11168 | 38.8% | 33.4% | 27.8% | 18.7% | 50.5% | 30.8% |
| 28 | Mark Buehrle | - - - | .294 | 1.25 | 18.9% | 45.1% | 36.0% | 9.2% | 9.1% | 661 | 4.76 | 6856 | 12362 | 19218 | 44.2% | 33.3% | 22.6% | 19.7% | 54.3% | 26.0% |
| 29 | Roy Halladay | - - - | .296 | 1.73 | 19.6% | 51.0% | 29.4% | 11.1% | 9.1% | 776 | 5.17 | 6376 | 13332 | 19708 | 40.8% | 35.3% | 23.9% | 21.7% | 54.1% | 24.2% |
| 30 | David Price | TBR | .275 | 1.30 | 18.5% | 46.0% | 35.5% | 9.4% | 9.1% | 451 | 5.16 | 4602 | 8298 | 12900 | 34.6% | 37.6% | 27.8% | 18.7% | 56.0% | 25.3% |