| 1 | Edwin Jackson | CHC | 6 | 15 | 0 | 28 | 27 | 140.2 | 7.87 | 4.03 | 1.15 | .352 | 61.8% | 39.4% | 11.9% | 93.8 | 6.33 | | 4.45 | 4.12 | 0.7 |
| 2 | Robbie Ross Jr. | TEX | 3 | 6 | 0 | 27 | 12 | 78.1 | 5.86 | 3.45 | 1.03 | .351 | 58.9% | 53.5% | 12.2% | 91.6 | 6.20 | | 4.74 | 4.41 | -0.1 |
| 3 | Jacob Turner | - - - | 6 | 11 | 0 | 28 | 18 | 113.0 | 5.65 | 2.63 | 0.96 | .354 | 61.1% | 49.1% | 10.3% | 93.0 | 6.13 | | 4.16 | 4.05 | 0.5 |
| 4 | Justin Masterson | - - - | 7 | 9 | 0 | 28 | 25 | 128.2 | 8.11 | 4.83 | 0.84 | .339 | 64.8% | 58.2% | 14.6% | 90.7 | 5.88 | | 4.50 | 4.08 | 0.5 |
| 5 | Trevor Cahill | ARI | 3 | 12 | 1 | 32 | 17 | 110.2 | 8.54 | 4.47 | 0.73 | .350 | 62.6% | 48.5% | 10.1% | 92.0 | 5.61 | | 3.89 | 3.83 | 0.6 |
| 6 | Felix Doubront | - - - | 4 | 5 | 0 | 21 | 14 | 79.2 | 5.76 | 3.73 | 1.36 | .297 | 65.9% | 38.0% | 11.2% | 90.5 | 5.54 | | 5.13 | 4.83 | -0.2 |
| 7 | Scott Baker | TEX | 3 | 4 | 0 | 25 | 8 | 80.2 | 6.14 | 1.56 | 1.67 | .272 | 63.6% | 25.3% | 11.5% | 90.3 | 5.47 | | 4.78 | 4.37 | 0.1 |
| 8 | Kevin Correia | - - - | 7 | 17 | 0 | 32 | 26 | 154.0 | 4.62 | 2.34 | 1.17 | .315 | 63.5% | 43.2% | 9.5% | 90.8 | 5.44 | | 4.67 | 4.67 | 0.4 |
| 9 | Juan Nicasio | COL | 6 | 6 | 0 | 33 | 14 | 93.2 | 6.05 | 2.98 | 1.83 | .298 | 71.2% | 45.9% | 18.3% | 93.5 | 5.38 | | 5.45 | 4.18 | -0.4 |
| 10 | Ricky Nolasco | MIN | 6 | 12 | 0 | 27 | 27 | 159.0 | 6.51 | 2.15 | 1.25 | .351 | 69.7% | 41.8% | 11.6% | 91.3 | 5.38 | | 4.30 | 3.97 | 1.3 |
| 11 | Franklin Morales | COL | 6 | 9 | 0 | 38 | 22 | 142.1 | 6.32 | 4.11 | 1.52 | .315 | 72.3% | 42.8% | 15.9% | 92.1 | 5.37 | | 5.42 | 4.53 | -0.4 |
| 12 | Clay Buchholz | BOS | 8 | 11 | 0 | 28 | 28 | 170.1 | 6.97 | 2.85 | 0.90 | .315 | 62.1% | 46.6% | 9.2% | 92.7 | 5.34 | | 4.01 | 4.04 | 1.3 |
| 13 | Erasmo Ramirez | SEA | 1 | 6 | 0 | 17 | 14 | 75.1 | 7.17 | 4.06 | 1.55 | .307 | 75.1% | 37.7% | 12.7% | 92.1 | 5.26 | | 5.38 | 4.81 | -0.5 |
| 14 | Chase Whitley | NYY | 4 | 3 | 0 | 24 | 12 | 75.2 | 7.14 | 2.14 | 1.19 | .353 | 70.6% | 45.3% | 12.0% | 91.5 | 5.23 | | 4.14 | 3.77 | 0.5 |
| 15 | Zach McAllister | CLE | 4 | 7 | 0 | 22 | 15 | 86.0 | 7.74 | 2.93 | 0.73 | .332 | 61.3% | 42.1% | 6.9% | 94.0 | 5.23 | | 3.45 | 3.84 | 1.4 |
| 16 | Colby Lewis | TEX | 10 | 14 | 0 | 29 | 29 | 170.1 | 7.03 | 2.54 | 1.32 | .339 | 69.0% | 33.0% | 10.1% | 89.7 | 5.18 | | 4.46 | 4.36 | 1.2 |
| 17 | Brandon Workman | BOS | 1 | 10 | 0 | 19 | 15 | 87.0 | 7.24 | 3.72 | 1.14 | .296 | 62.0% | 41.2% | 11.2% | 91.1 | 5.17 | | 4.44 | 4.19 | 0.3 |
| 18 | Travis Wood | CHC | 8 | 13 | 0 | 31 | 31 | 173.2 | 7.57 | 3.94 | 1.04 | .320 | 66.5% | 34.4% | 8.8% | 89.6 | 5.03 | | 4.38 | 4.51 | 1.4 |
| 19 | Brandon Cumpton | PIT | 3 | 4 | 0 | 16 | 10 | 70.0 | 5.91 | 2.31 | 0.26 | .338 | 63.0% | 44.2% | 3.1% | 93.6 | 4.89 | | 3.22 | 3.98 | 0.9 |
| 20 | Randall Delgado | ARI | 4 | 4 | 0 | 47 | 4 | 77.2 | 9.97 | 4.06 | 0.70 | .311 | 64.6% | 35.2% | 6.5% | 94.2 | 4.87 | | 3.39 | 3.85 | 0.5 |
| 21 | Paul Maholm | LAD | 1 | 5 | 0 | 30 | 8 | 70.2 | 4.33 | 3.57 | 1.02 | .311 | 67.8% | 54.4% | 12.9% | 88.4 | 4.84 | | 4.96 | 4.57 | -0.5 |
| 22 | Ubaldo Jimenez | BAL | 6 | 9 | 0 | 25 | 22 | 125.1 | 8.33 | 5.53 | 1.01 | .289 | 72.2% | 41.3% | 10.9% | 92.1 | 4.81 | | 4.67 | 4.48 | 0.4 |
| 23 | Scott Carroll | CHW | 5 | 10 | 0 | 26 | 19 | 129.1 | 4.45 | 3.13 | 0.90 | .305 | 66.2% | 53.4% | 11.1% | 90.4 | 4.80 | | 4.77 | 4.58 | 0.1 |
| 24 | Jerome Williams | - - - | 6 | 7 | 0 | 37 | 11 | 115.0 | 6.42 | 2.82 | 0.94 | .313 | 68.6% | 44.6% | 10.0% | 92.2 | 4.77 | | 4.16 | 4.09 | 0.3 |
| 25 | Mike Minor | ATL | 6 | 12 | 0 | 25 | 25 | 145.1 | 7.43 | 2.72 | 1.30 | .323 | 74.4% | 40.6% | 12.9% | 91.7 | 4.77 | | 4.39 | 3.90 | 0.4 |
| 26 | Josh Tomlin | CLE | 6 | 9 | 0 | 25 | 16 | 104.0 | 8.13 | 1.21 | 1.56 | .320 | 62.8% | 37.5% | 15.3% | 89.8 | 4.76 | | 4.01 | 3.16 | 1.0 |
| 27 | Erik Bedard | TBR | 4 | 6 | 0 | 17 | 15 | 75.2 | 7.61 | 3.45 | 1.19 | .312 | 68.3% | 33.6% | 9.0% | 89.3 | 4.76 | | 4.39 | 4.48 | 0.1 |
| 28 | Hector Noesi | - - - | 8 | 12 | 0 | 33 | 27 | 172.1 | 6.42 | 2.92 | 1.46 | .290 | 70.4% | 38.0% | 12.7% | 93.7 | 4.75 | | 4.83 | 4.29 | 0.2 |
| 29 | Tim Lincecum | SFG | 12 | 9 | 1 | 33 | 26 | 155.2 | 7.75 | 3.64 | 1.10 | .299 | 69.6% | 47.3% | 13.9% | 90.3 | 4.74 | | 4.31 | 3.81 | 0.0 |
| 30 | John Danks | CHW | 11 | 11 | 0 | 32 | 32 | 193.2 | 5.99 | 3.44 | 1.16 | .291 | 71.9% | 42.3% | 10.4% | 89.3 | 4.74 | | 4.76 | 4.62 | 0.5 |