| 1 | Dallas Keuchel | HOU | 12 | 9 | 0 | 29 | 29 | 200.0 | 6.57 | 2.16 | 0.49 | .295 | 75.5% | 63.5% | 9.6% | 90.2 | 2.92 | | 3.21 | 3.20 | 3.5 |
| 2 | T.J. House | CLE | 5 | 3 | 0 | 19 | 18 | 102.0 | 7.06 | 1.94 | 0.88 | .332 | 78.9% | 60.9% | 17.9% | 92.2 | 3.35 | | 3.69 | 3.10 | 1.1 |
| 3 | Justin Masterson | - - - | 7 | 9 | 0 | 28 | 25 | 128.2 | 8.11 | 4.83 | 0.84 | .339 | 64.8% | 58.2% | 14.6% | 90.7 | 5.88 | | 4.50 | 4.08 | 0.5 |
| 4 | Tyson Ross | SDP | 13 | 14 | 0 | 31 | 31 | 195.2 | 8.97 | 3.31 | 0.60 | .291 | 75.1% | 57.0% | 11.3% | 94.5 | 2.81 | | 3.24 | 3.11 | 2.6 |
| 5 | Dan Otero | OAK | 8 | 2 | 1 | 72 | 0 | 86.2 | 4.67 | 1.56 | 0.42 | .270 | 79.9% | 56.4% | 7.1% | 91.2 | 2.28 | | 3.28 | 3.48 | 0.7 |
| 6 | Felix Hernandez | SEA | 15 | 6 | 0 | 34 | 34 | 236.0 | 9.46 | 1.75 | 0.61 | .258 | 77.0% | 56.2% | 10.1% | 93.6 | 2.14 | | 2.56 | 2.51 | 5.6 |
| 7 | Alex Cobb | TBR | 10 | 9 | 0 | 27 | 27 | 166.1 | 8.06 | 2.54 | 0.60 | .282 | 77.9% | 56.2% | 8.5% | 92.7 | 2.87 | | 3.23 | 3.33 | 2.5 |
| 8 | David Hale | ATL | 4 | 5 | 0 | 45 | 6 | 87.1 | 4.53 | 4.02 | 0.52 | .288 | 75.0% | 56.0% | 6.8% | 92.0 | 3.30 | | 4.31 | 4.61 | 0.0 |
| 9 | Seth Maness | STL | 6 | 4 | 3 | 73 | 0 | 80.1 | 6.16 | 1.23 | 0.78 | .289 | 76.1% | 56.0% | 11.5% | 90.8 | 2.91 | | 3.38 | 3.19 | 0.5 |
| 10 | Sonny Gray | OAK | 14 | 10 | 0 | 33 | 33 | 219.0 | 7.52 | 3.04 | 0.62 | .277 | 74.5% | 55.9% | 9.4% | 94.3 | 3.08 | | 3.46 | 3.47 | 3.5 |
| 11 | Charlie Morton | PIT | 6 | 12 | 0 | 26 | 26 | 157.1 | 7.21 | 3.26 | 0.51 | .295 | 69.3% | 55.7% | 8.8% | 92.6 | 3.72 | | 3.72 | 3.78 | 1.3 |
| 12 | Joe Kelly | - - - | 6 | 4 | 0 | 17 | 17 | 96.1 | 6.17 | 3.92 | 0.75 | .274 | 70.7% | 54.9% | 11.4% | 95.8 | 4.20 | | 4.37 | 4.19 | 0.3 |
| 13 | Francisco Liriano | PIT | 7 | 10 | 0 | 29 | 29 | 162.1 | 9.70 | 4.49 | 0.72 | .280 | 74.7% | 54.4% | 11.6% | 93.6 | 3.38 | | 3.59 | 3.40 | 1.6 |
| 14 | Kyle Gibson | MIN | 13 | 12 | 0 | 31 | 31 | 179.1 | 5.37 | 2.86 | 0.60 | .287 | 66.3% | 54.4% | 7.8% | 92.6 | 4.47 | | 3.80 | 3.99 | 2.7 |
| 15 | Jarred Cosart | - - - | 13 | 11 | 0 | 30 | 30 | 180.1 | 5.74 | 3.64 | 0.45 | .290 | 71.5% | 54.2% | 6.0% | | 3.69 | | 3.77 | 4.15 | 2.0 |
| 16 | Zack Wheeler | NYM | 11 | 11 | 0 | 32 | 32 | 185.1 | 9.08 | 3.84 | 0.68 | .304 | 72.9% | 54.0% | 10.1% | 96.1 | 3.54 | | 3.55 | 3.49 | 2.4 |
| 17 | Marcus Stroman | TOR | 11 | 6 | 1 | 26 | 20 | 130.2 | 7.65 | 1.93 | 0.48 | .306 | 68.4% | 53.8% | 6.5% | 94.2 | 3.65 | | 2.84 | 3.17 | 3.4 |
| 18 | Henderson Alvarez | MIA | 12 | 7 | 0 | 30 | 30 | 187.0 | 5.34 | 1.59 | 0.67 | .304 | 79.3% | 53.8% | 9.5% | 94.4 | 2.65 | | 3.58 | 3.57 | 2.5 |
| 19 | Wily Peralta | MIL | 17 | 11 | 0 | 32 | 32 | 198.2 | 6.98 | 2.76 | 1.04 | .295 | 76.1% | 53.6% | 13.9% | 96.3 | 3.53 | | 4.11 | 3.64 | 1.5 |
| 20 | Bronson Arroyo | ARI | 7 | 4 | 0 | 14 | 14 | 86.0 | 4.92 | 1.99 | 1.05 | .295 | 74.0% | 53.6% | 13.3% | 86.1 | 4.08 | | 4.32 | 3.88 | 0.4 |
| 21 | Samuel Deduno | - - - | 2 | 6 | 0 | 35 | 9 | 100.2 | 7.42 | 4.11 | 0.80 | .298 | 71.2% | 53.5% | 11.4% | 90.4 | 4.47 | | 4.31 | 4.12 | 0.2 |
| 22 | Mike Leake | CIN | 11 | 13 | 0 | 33 | 33 | 214.1 | 6.89 | 2.10 | 0.97 | .298 | 75.5% | 53.4% | 13.1% | 91.9 | 3.70 | | 3.88 | 3.49 | 2.3 |
| 23 | Scott Carroll | CHW | 5 | 10 | 0 | 26 | 19 | 129.1 | 4.45 | 3.13 | 0.90 | .305 | 66.2% | 53.4% | 11.1% | 90.4 | 4.80 | | 4.77 | 4.58 | 0.1 |
| 24 | Tim Hudson | SFG | 9 | 13 | 0 | 31 | 31 | 189.1 | 5.70 | 1.62 | 0.71 | .300 | 70.3% | 53.1% | 9.3% | 89.9 | 3.57 | | 3.54 | 3.57 | 1.7 |
| 25 | Brandon McCarthy | - - - | 10 | 15 | 0 | 32 | 32 | 200.0 | 7.88 | 1.49 | 1.13 | .328 | 70.9% | 52.6% | 16.3% | 93.9 | 4.05 | | 3.55 | 2.87 | 2.6 |
| 26 | Carlos Carrasco | CLE | 8 | 7 | 1 | 40 | 14 | 134.0 | 9.40 | 1.95 | 0.47 | .274 | 75.9% | 52.5% | 7.1% | 96.1 | 2.55 | | 2.44 | 2.66 | 3.2 |
| 27 | Odrisamer Despaigne | SDP | 4 | 7 | 0 | 16 | 16 | 96.1 | 6.07 | 2.99 | 0.56 | .267 | 68.7% | 52.1% | 7.1% | 91.3 | 3.36 | | 3.74 | 4.01 | 0.8 |
| 28 | Clayton Kershaw | LAD | 21 | 3 | 0 | 27 | 27 | 198.1 | 10.85 | 1.41 | 0.41 | .278 | 81.6% | 51.8% | 6.6% | 93.7 | 1.77 | | 1.81 | 2.08 | 7.9 |
| 29 | Jordan Lyles | COL | 7 | 4 | 0 | 22 | 22 | 126.2 | 6.39 | 3.27 | 0.85 | .295 | 71.3% | 51.7% | 11.9% | 92.5 | 4.33 | | 4.22 | 3.98 | 1.4 |
| 30 | Jorge De La Rosa | COL | 14 | 11 | 0 | 32 | 32 | 184.1 | 6.79 | 3.27 | 1.03 | .263 | 70.8% | 51.6% | 12.9% | 93.1 | 4.10 | | 4.34 | 3.95 | 1.7 |