| 1 | Jose Fernandez | MIA | 16 | 8 | 0 | 29 | 29 | 182.1 | 12.49 | 2.71 | 0.64 | .332 | 76.6% | 40.2% | 10.0% | 96.0 | 2.86 | 3.00 | 2.30 | 2.56 | 6.3 |
| 2 | Noah Syndergaard | NYM | 14 | 9 | 0 | 31 | 30 | 183.2 | 10.68 | 2.11 | 0.54 | .334 | 76.9% | 51.2% | 8.6% | 98.9 | 2.60 | 2.78 | 2.29 | 2.67 | 6.0 |
| 3 | Max Scherzer | WSN | 20 | 7 | 0 | 34 | 34 | 228.1 | 11.19 | 2.21 | 1.22 | .255 | 81.7% | 33.0% | 11.9% | 95.1 | 2.96 | 2.78 | 3.24 | 3.37 | 5.6 |
| 4 | Justin Verlander | DET | 16 | 9 | 0 | 34 | 34 | 227.2 | 10.04 | 2.25 | 1.19 | .255 | 79.9% | 33.7% | 10.9% | 94.2 | 3.04 | 3.12 | 3.48 | 3.78 | 5.4 |
| 5 | Chris Sale | CHW | 17 | 10 | 0 | 32 | 32 | 226.2 | 9.25 | 1.79 | 1.07 | .279 | 76.6% | 41.2% | 11.9% | 93.8 | 3.34 | 3.61 | 3.46 | 3.58 | 5.3 |
| 6 | Rick Porcello | BOS | 22 | 4 | 0 | 33 | 33 | 223.0 | 7.63 | 1.29 | 0.93 | .269 | 74.3% | 43.1% | 9.3% | 92.4 | 3.15 | 3.80 | 3.40 | 3.89 | 5.1 |
| 7 | Jose Quintana | CHW | 13 | 12 | 0 | 32 | 32 | 208.0 | 7.83 | 2.16 | 0.95 | .293 | 79.0% | 40.4% | 9.5% | 92.7 | 3.20 | 3.61 | 3.56 | 4.03 | 4.9 |
| 8 | Corey Kluber | CLE | 18 | 9 | 0 | 32 | 32 | 215.0 | 9.50 | 2.39 | 0.92 | .271 | 74.8% | 44.5% | 10.8% | 93.1 | 3.14 | 3.31 | 3.26 | 3.50 | 4.9 |
| 9 | Johnny Cueto | SFG | 18 | 5 | 0 | 32 | 32 | 219.2 | 8.11 | 1.84 | 0.61 | .293 | 78.0% | 50.2% | 8.4% | 92.5 | 2.79 | 3.53 | 2.96 | 3.42 | 4.9 |
| 10 | Masahiro Tanaka | NYY | 14 | 4 | 0 | 31 | 31 | 199.2 | 7.44 | 1.62 | 0.99 | .271 | 76.4% | 48.2% | 12.0% | 92.1 | 3.07 | 3.59 | 3.51 | 3.61 | 4.7 |
| 11 | David Price | BOS | 17 | 9 | 0 | 35 | 35 | 230.0 | 8.92 | 1.96 | 1.17 | .310 | 73.6% | 43.7% | 13.5% | 93.8 | 3.99 | 3.72 | 3.60 | 3.52 | 4.4 |
| 12 | Madison Bumgarner | SFG | 15 | 9 | 0 | 34 | 34 | 226.2 | 9.97 | 2.14 | 1.03 | .265 | 79.1% | 39.6% | 10.7% | 91.6 | 2.74 | 3.24 | 3.24 | 3.54 | 4.3 |
| 13 | Jon Lester | CHC | 19 | 5 | 0 | 32 | 32 | 202.2 | 8.75 | 2.31 | 0.93 | .256 | 84.9% | 46.9% | 12.2% | 93.1 | 2.44 | 3.07 | 3.41 | 3.47 | 4.2 |
| 14 | Kyle Hendricks | CHC | 16 | 8 | 0 | 31 | 30 | 190.0 | 8.05 | 2.08 | 0.71 | .250 | 81.5% | 48.4% | 9.3% | 88.9 | 2.13 | 2.78 | 3.20 | 3.59 | 4.2 |
| 15 | Jon Gray | COL | 10 | 10 | 0 | 29 | 29 | 168.0 | 9.91 | 3.16 | 0.96 | .308 | 66.4% | 43.5% | 12.8% | 95.8 | 4.61 | 4.05 | 3.60 | 3.61 | 3.6 |
| 16 | Ervin Santana | MIN | 7 | 11 | 0 | 30 | 30 | 181.1 | 7.40 | 2.63 | 0.94 | .285 | 74.1% | 42.6% | 9.9% | 93.6 | 3.38 | 4.13 | 3.81 | 4.21 | 3.5 |
| 17 | Aaron Sanchez | TOR | 15 | 2 | 0 | 30 | 30 | 192.0 | 7.55 | 2.95 | 0.70 | .267 | 76.9% | 54.4% | 10.7% | 95.4 | 3.00 | 4.13 | 3.55 | 3.75 | 3.5 |
| 18 | Jake Arrieta | CHC | 18 | 8 | 0 | 31 | 31 | 197.1 | 8.67 | 3.47 | 0.73 | .241 | 74.9% | 52.6% | 11.1% | 94.4 | 3.10 | 3.56 | 3.52 | 3.68 | 3.5 |
| 19 | Jeremy Hellickson | PHI | 12 | 10 | 0 | 32 | 32 | 189.0 | 7.33 | 2.14 | 1.14 | .274 | 72.5% | 40.7% | 12.7% | 90.9 | 3.71 | 4.43 | 3.98 | 3.99 | 3.4 |
| 20 | Cole Hamels | TEX | 15 | 5 | 0 | 32 | 32 | 200.2 | 8.97 | 3.45 | 1.08 | .299 | 79.1% | 49.6% | 14.0% | 93.4 | 3.32 | 4.19 | 3.98 | 3.85 | 3.3 |
| 21 | Marcus Stroman | TOR | 9 | 10 | 0 | 32 | 32 | 204.0 | 7.32 | 2.38 | 0.93 | .308 | 68.6% | 60.1% | 16.5% | 93.7 | 4.37 | 3.93 | 3.71 | 3.41 | 3.3 |
| 22 | Tanner Roark | WSN | 16 | 10 | 0 | 34 | 33 | 210.0 | 7.37 | 3.13 | 0.73 | .269 | 79.5% | 48.7% | 9.4% | 93.0 | 2.83 | 3.93 | 3.79 | 4.17 | 3.3 |
| 23 | Robbie Ray | ARI | 8 | 15 | 0 | 32 | 32 | 174.1 | 11.25 | 3.67 | 1.24 | .352 | 68.7% | 45.7% | 15.5% | 95.0 | 4.90 | 4.25 | 3.76 | 3.45 | 3.3 |
| 24 | Michael Pineda | NYY | 6 | 12 | 0 | 32 | 32 | 175.2 | 10.61 | 2.72 | 1.38 | .339 | 70.7% | 45.8% | 17.0% | 94.7 | 4.82 | 3.88 | 3.80 | 3.30 | 3.2 |
| 25 | Carlos Martinez | STL | 16 | 9 | 0 | 31 | 31 | 195.1 | 8.02 | 3.23 | 0.69 | .286 | 79.5% | 56.4% | 10.6% | 97.2 | 3.04 | 3.33 | 3.61 | 3.81 | 3.2 |
| 26 | Kevin Gausman | BAL | 9 | 12 | 0 | 30 | 30 | 179.2 | 8.72 | 2.35 | 1.40 | .308 | 81.2% | 44.1% | 15.4% | 95.4 | 3.61 | 4.16 | 4.10 | 3.77 | 3.1 |
| 27 | Julio Teheran | ATL | 7 | 10 | 0 | 30 | 30 | 188.0 | 7.99 | 1.96 | 1.05 | .260 | 77.8% | 39.1% | 10.0% | 91.7 | 3.21 | 3.72 | 3.69 | 4.13 | 3.0 |
| 28 | Jerad Eickhoff | PHI | 11 | 14 | 0 | 33 | 33 | 197.1 | 7.62 | 1.92 | 1.37 | .278 | 76.4% | 40.7% | 13.1% | 91.5 | 3.65 | 3.59 | 4.19 | 4.15 | 3.0 |
| 29 | Drew Pomeranz | - - - | 11 | 12 | 0 | 31 | 30 | 170.2 | 9.81 | 3.43 | 1.16 | .268 | 80.1% | 46.2% | 13.6% | 91.8 | 3.32 | 3.24 | 3.80 | 3.71 | 3.0 |
| 30 | Chris Archer | TBR | 9 | 19 | 0 | 33 | 33 | 201.1 | 10.42 | 3.00 | 1.34 | .296 | 72.5% | 47.8% | 16.2% | 95.1 | 4.02 | 3.82 | 3.81 | 3.41 | 2.9 |