| 1 | Dakota Hudson | STL | 16 | 7 | 1 | 33 | 32 | 174.2 | 7.01 | 4.43 | 1.13 | .274 | 78.1% | 56.9% | 19.8% | 94.1 | 3.35 | 5.09 | 4.93 | 4.55 | 0.9 |
| 2 | Luis Castillo | CIN | 15 | 8 | 0 | 32 | 32 | 190.2 | 10.67 | 3.73 | 1.04 | .262 | 76.7% | 55.2% | 17.9% | 96.3 | 3.40 | 3.36 | 3.70 | 3.48 | 4.2 |
| 3 | Brett Anderson | OAK | 13 | 9 | 0 | 31 | 31 | 176.0 | 4.60 | 2.51 | 1.02 | .278 | 74.8% | 54.5% | 13.3% | 91.2 | 3.89 | 5.44 | 4.57 | 4.79 | 2.0 |
| 4 | Marcus Stroman | - - - | 10 | 13 | 0 | 32 | 32 | 184.1 | 7.76 | 2.83 | 0.88 | .307 | 76.1% | 53.7% | 12.6% | 93.1 | 3.22 | 3.72 | 3.72 | 3.99 | 3.8 |
| 5 | Max Fried | ATL | 17 | 6 | 0 | 33 | 30 | 165.2 | 9.40 | 2.55 | 1.14 | .336 | 74.3% | 53.6% | 20.2% | 93.9 | 4.02 | 3.86 | 3.72 | 3.32 | 3.0 |
| 6 | Mike Soroka | ATL | 13 | 4 | 0 | 29 | 29 | 174.2 | 7.32 | 2.11 | 0.72 | .280 | 79.9% | 51.2% | 11.1% | 92.9 | 2.68 | 4.11 | 3.45 | 3.85 | 4.0 |
| 7 | Stephen Strasburg | WSN | 18 | 6 | 0 | 33 | 33 | 209.0 | 10.81 | 2.41 | 1.03 | .274 | 76.5% | 51.1% | 16.2% | 94.1 | 3.32 | 3.09 | 3.25 | 3.17 | 5.6 |
| 8 | Sonny Gray | CIN | 11 | 8 | 0 | 31 | 31 | 175.1 | 10.52 | 3.49 | 0.87 | .255 | 79.7% | 50.8% | 13.0% | 93.4 | 2.87 | 3.56 | 3.42 | 3.65 | 4.5 |
| 9 | Hyun-Jin Ryu | LAD | 14 | 5 | 0 | 29 | 29 | 182.2 | 8.03 | 1.18 | 0.84 | .278 | 82.2% | 50.4% | 13.0% | 90.9 | 2.32 | 3.43 | 3.10 | 3.32 | 4.9 |
| 10 | Brad Keller | KCR | 7 | 14 | 0 | 28 | 28 | 165.1 | 6.64 | 3.81 | 0.82 | .282 | 72.2% | 50.0% | 10.2% | 93.8 | 4.19 | 4.82 | 4.35 | 4.94 | 2.2 |
| 11 | Aaron Nola | PHI | 12 | 7 | 0 | 34 | 34 | 202.1 | 10.19 | 3.56 | 1.20 | .295 | 76.8% | 49.7% | 17.4% | 93.3 | 3.87 | 4.23 | 4.03 | 3.82 | 3.4 |
| 12 | Wade Miley | HOU | 14 | 6 | 0 | 33 | 33 | 167.1 | 7.53 | 3.28 | 1.24 | .287 | 74.3% | 49.7% | 15.2% | 90.9 | 3.98 | 4.14 | 4.51 | 4.52 | 2.0 |
| 13 | Patrick Corbin | WSN | 14 | 7 | 0 | 33 | 33 | 202.0 | 10.60 | 3.12 | 1.07 | .290 | 77.3% | 49.5% | 14.4% | 92.0 | 3.25 | 4.06 | 3.49 | 3.59 | 4.7 |
| 14 | German Marquez | COL | 12 | 5 | 0 | 28 | 28 | 174.0 | 9.05 | 1.81 | 1.50 | .304 | 68.1% | 49.0% | 20.1% | 95.7 | 4.76 | 4.79 | 4.06 | 3.54 | 3.3 |
| 15 | Adam Wainwright | STL | 14 | 10 | 0 | 31 | 31 | 171.2 | 8.02 | 3.36 | 1.15 | .319 | 76.5% | 48.8% | 15.0% | 89.8 | 4.19 | 4.82 | 4.36 | 4.39 | 2.1 |
| 16 | Eduardo Rodriguez | BOS | 19 | 6 | 0 | 34 | 34 | 203.1 | 9.43 | 3.32 | 1.06 | .317 | 77.6% | 48.5% | 13.3% | 93.1 | 3.81 | 3.75 | 3.86 | 4.10 | 3.7 |
| 17 | Charlie Morton | TBR | 16 | 6 | 0 | 33 | 33 | 194.2 | 11.10 | 2.64 | 0.69 | .298 | 75.2% | 48.2% | 10.4% | 94.8 | 3.05 | 3.26 | 2.81 | 3.28 | 6.0 |
| 18 | Noah Syndergaard | NYM | 10 | 8 | 0 | 32 | 32 | 197.2 | 9.20 | 2.28 | 1.09 | .313 | 68.9% | 48.0% | 13.3% | 97.9 | 4.28 | 3.41 | 3.60 | 3.83 | 4.3 |
| 19 | Clayton Kershaw | LAD | 16 | 5 | 0 | 29 | 28 | 178.1 | 9.54 | 2.07 | 1.41 | .262 | 84.0% | 48.0% | 18.5% | 90.4 | 3.03 | 3.64 | 3.86 | 3.50 | 3.6 |
| 20 | Martin Perez | MIN | 10 | 7 | 0 | 32 | 29 | 165.1 | 7.35 | 3.65 | 1.25 | .316 | 67.6% | 48.0% | 15.0% | 94.2 | 5.12 | 4.11 | 4.66 | 4.69 | 1.9 |
| 21 | Masahiro Tanaka | NYY | 11 | 9 | 0 | 32 | 31 | 182.0 | 7.37 | 1.98 | 1.38 | .293 | 70.4% | 47.5% | 15.1% | 91.5 | 4.45 | 4.35 | 4.27 | 4.29 | 3.2 |
| 22 | Miles Mikolas | STL | 9 | 14 | 0 | 32 | 32 | 184.0 | 7.04 | 1.57 | 1.32 | .302 | 73.8% | 47.4% | 16.1% | 93.8 | 4.16 | 4.86 | 4.27 | 4.18 | 2.4 |
| 23 | Joey Lucchesi | SDP | 10 | 10 | 0 | 30 | 30 | 163.2 | 8.69 | 3.08 | 1.26 | .271 | 73.0% | 47.0% | 13.9% | 90.6 | 4.18 | 3.86 | 4.17 | 4.36 | 2.1 |
| 24 | Mike Leake | - - - | 12 | 11 | 0 | 32 | 32 | 197.0 | 5.80 | 1.23 | 1.87 | .295 | 72.6% | 46.8% | 18.2% | 88.8 | 4.29 | 5.74 | 5.19 | 4.76 | 0.9 |
| 25 | Ivan Nova | CHW | 11 | 12 | 0 | 34 | 34 | 187.0 | 5.49 | 2.26 | 1.44 | .322 | 72.8% | 46.1% | 15.8% | 92.6 | 4.72 | 5.63 | 4.98 | 4.91 | 2.1 |
| 26 | Yu Darvish | CHC | 6 | 8 | 0 | 31 | 31 | 178.2 | 11.54 | 2.82 | 1.66 | .266 | 77.7% | 45.5% | 22.8% | 94.3 | 3.98 | 3.89 | 4.18 | 3.39 | 2.6 |
| 27 | Zack Greinke | - - - | 18 | 5 | 0 | 33 | 33 | 208.2 | 8.07 | 1.29 | 0.91 | .271 | 75.7% | 45.2% | 10.9% | 89.9 | 2.93 | 3.46 | 3.22 | 3.74 | 5.3 |
| 28 | Sandy Alcantara | MIA | 6 | 14 | 0 | 32 | 32 | 197.1 | 6.89 | 3.69 | 1.05 | .271 | 73.8% | 44.6% | 10.8% | 95.7 | 3.88 | 4.60 | 4.55 | 5.17 | 2.3 |
| 29 | Joe Musgrove | PIT | 11 | 12 | 0 | 32 | 31 | 170.1 | 8.30 | 2.06 | 1.11 | .299 | 63.2% | 44.5% | 11.7% | 92.7 | 4.44 | 4.17 | 3.82 | 4.31 | 3.3 |
| 30 | Jose Quintana | CHC | 13 | 9 | 0 | 32 | 31 | 171.0 | 8.00 | 2.42 | 1.05 | .326 | 65.9% | 44.5% | 12.1% | 91.5 | 4.68 | 4.73 | 3.80 | 4.20 | 3.5 |