| 1 | Justin Verlander | HOU | 21 | 6 | 0 | 34 | 34 | 223.0 | 12.11 | 1.70 | 1.45 | .218 | 88.4% | 35.9% | 16.0% | 94.6 | 2.58 | 2.66 | 3.27 | 3.18 | 6.4 |
| 2 | Eduardo Rodriguez | BOS | 19 | 6 | 0 | 34 | 34 | 203.1 | 9.43 | 3.32 | 1.06 | .317 | 77.6% | 48.5% | 13.3% | 93.1 | 3.81 | 3.75 | 3.86 | 4.10 | 3.7 |
| 3 | Marco Gonzales | SEA | 16 | 13 | 0 | 34 | 34 | 203.0 | 6.52 | 2.48 | 1.02 | .295 | 69.2% | 40.7% | 9.3% | 89.1 | 3.99 | 4.26 | 4.15 | 5.11 | 3.6 |
| 4 | Aaron Nola | PHI | 12 | 7 | 0 | 34 | 34 | 202.1 | 10.19 | 3.56 | 1.20 | .295 | 76.8% | 49.7% | 17.4% | 93.3 | 3.87 | 4.23 | 4.03 | 3.82 | 3.4 |
| 5 | Madison Bumgarner | SFG | 9 | 9 | 0 | 34 | 34 | 207.2 | 8.80 | 1.86 | 1.30 | .289 | 71.8% | 35.8% | 12.6% | 91.6 | 3.90 | 4.57 | 3.90 | 4.31 | 3.3 |
| 6 | Trevor Bauer | - - - | 11 | 13 | 0 | 34 | 34 | 213.0 | 10.69 | 3.46 | 1.44 | .287 | 70.3% | 37.6% | 15.3% | 94.6 | 4.48 | 4.23 | 4.34 | 4.33 | 3.2 |
| 7 | Ivan Nova | CHW | 11 | 12 | 0 | 34 | 34 | 187.0 | 5.49 | 2.26 | 1.44 | .322 | 72.8% | 46.1% | 15.8% | 92.6 | 4.72 | 5.63 | 4.98 | 4.91 | 2.1 |
| 8 | Gerrit Cole | HOU | 20 | 5 | 0 | 33 | 33 | 212.1 | 13.82 | 2.03 | 1.23 | .275 | 83.3% | 40.3% | 16.9% | 97.3 | 2.50 | 2.45 | 2.64 | 2.48 | 7.5 |
| 9 | Lance Lynn | TEX | 16 | 11 | 0 | 33 | 33 | 208.1 | 10.63 | 2.55 | 0.91 | .322 | 74.4% | 40.3% | 9.9% | 94.7 | 3.67 | 3.48 | 3.13 | 3.85 | 6.8 |
| 10 | Charlie Morton | TBR | 16 | 6 | 0 | 33 | 33 | 194.2 | 11.10 | 2.64 | 0.69 | .298 | 75.2% | 48.2% | 10.4% | 94.8 | 3.05 | 3.26 | 2.81 | 3.28 | 6.0 |
| 11 | Stephen Strasburg | WSN | 18 | 6 | 0 | 33 | 33 | 209.0 | 10.81 | 2.41 | 1.03 | .274 | 76.5% | 51.1% | 16.2% | 94.1 | 3.32 | 3.09 | 3.25 | 3.17 | 5.6 |
| 12 | Shane Bieber | CLE | 15 | 8 | 0 | 34 | 33 | 214.1 | 10.88 | 1.68 | 1.30 | .296 | 77.4% | 43.9% | 16.1% | 93.2 | 3.28 | 3.83 | 3.32 | 3.23 | 5.5 |
| 13 | Zack Greinke | - - - | 18 | 5 | 0 | 33 | 33 | 208.2 | 8.07 | 1.29 | 0.91 | .271 | 75.7% | 45.2% | 10.9% | 89.9 | 2.93 | 3.46 | 3.22 | 3.74 | 5.3 |
| 14 | Patrick Corbin | WSN | 14 | 7 | 0 | 33 | 33 | 202.0 | 10.60 | 3.12 | 1.07 | .290 | 77.3% | 49.5% | 14.4% | 92.0 | 3.25 | 4.06 | 3.49 | 3.59 | 4.7 |
| 15 | Jack Flaherty | STL | 11 | 8 | 0 | 33 | 33 | 196.1 | 10.59 | 2.52 | 1.15 | .242 | 83.3% | 39.5% | 13.8% | 94.5 | 2.75 | 3.38 | 3.46 | 3.64 | 4.7 |
| 16 | Reynaldo Lopez | CHW | 10 | 15 | 0 | 33 | 33 | 184.0 | 8.27 | 3.18 | 1.71 | .316 | 69.2% | 35.0% | 14.0% | 95.5 | 5.38 | 5.13 | 5.04 | 5.27 | 2.4 |
| 17 | Robbie Ray | ARI | 12 | 8 | 0 | 33 | 33 | 174.1 | 12.13 | 4.34 | 1.55 | .305 | 75.1% | 37.0% | 20.0% | 92.5 | 4.34 | 4.60 | 4.29 | 3.76 | 2.3 |
| 18 | Wade Miley | HOU | 14 | 6 | 0 | 33 | 33 | 167.1 | 7.53 | 3.28 | 1.24 | .287 | 74.3% | 49.7% | 15.2% | 90.9 | 3.98 | 4.14 | 4.51 | 4.52 | 2.0 |
| 19 | Mike Fiers | OAK | 15 | 4 | 0 | 33 | 33 | 184.2 | 6.14 | 2.58 | 1.46 | .254 | 78.5% | 39.9% | 13.8% | 90.5 | 3.90 | 5.06 | 4.97 | 5.19 | 1.7 |
| 20 | Julio Teheran | ATL | 10 | 11 | 0 | 33 | 33 | 174.2 | 8.35 | 4.28 | 1.13 | .266 | 76.6% | 39.0% | 11.2% | 89.8 | 3.81 | 4.76 | 4.66 | 5.26 | 1.6 |
| 21 | Jacob deGrom | NYM | 11 | 8 | 0 | 32 | 32 | 204.0 | 11.25 | 1.94 | 0.84 | .282 | 81.8% | 44.4% | 11.2% | 97.1 | 2.43 | 2.70 | 2.67 | 3.11 | 6.9 |
| 22 | Jose Berrios | MIN | 14 | 8 | 0 | 32 | 32 | 200.1 | 8.76 | 2.29 | 1.17 | .299 | 73.5% | 42.1% | 12.0% | 93.3 | 3.68 | 4.06 | 3.85 | 4.32 | 4.4 |
| 23 | Noah Syndergaard | NYM | 10 | 8 | 0 | 32 | 32 | 197.2 | 9.20 | 2.28 | 1.09 | .313 | 68.9% | 48.0% | 13.3% | 97.9 | 4.28 | 3.41 | 3.60 | 3.83 | 4.3 |
| 24 | Luis Castillo | CIN | 15 | 8 | 0 | 32 | 32 | 190.2 | 10.67 | 3.73 | 1.04 | .262 | 76.7% | 55.2% | 17.9% | 96.3 | 3.40 | 3.36 | 3.70 | 3.48 | 4.2 |
| 25 | Mike Minor | TEX | 14 | 10 | 0 | 32 | 32 | 208.1 | 8.64 | 2.94 | 1.30 | .287 | 80.3% | 40.0% | 12.9% | 92.5 | 3.59 | 3.89 | 4.25 | 4.60 | 4.1 |
| 26 | Marcus Stroman | - - - | 10 | 13 | 0 | 32 | 32 | 184.1 | 7.76 | 2.83 | 0.88 | .307 | 76.1% | 53.7% | 12.6% | 93.1 | 3.22 | 3.72 | 3.72 | 3.99 | 3.8 |
| 27 | Matthew Boyd | DET | 9 | 12 | 0 | 32 | 32 | 185.1 | 11.56 | 2.43 | 1.89 | .307 | 74.4% | 35.6% | 18.2% | 92.2 | 4.56 | 3.83 | 4.32 | 3.88 | 3.2 |
| 28 | Miles Mikolas | STL | 9 | 14 | 0 | 32 | 32 | 184.0 | 7.04 | 1.57 | 1.32 | .302 | 73.8% | 47.4% | 16.1% | 93.8 | 4.16 | 4.86 | 4.27 | 4.18 | 2.4 |
| 29 | Sandy Alcantara | MIA | 6 | 14 | 0 | 32 | 32 | 197.1 | 6.89 | 3.69 | 1.05 | .271 | 73.8% | 44.6% | 10.8% | 95.7 | 3.88 | 4.60 | 4.55 | 5.17 | 2.3 |
| 30 | Merrill Kelly | ARI | 13 | 14 | 0 | 32 | 32 | 183.1 | 7.76 | 2.80 | 1.42 | .292 | 73.1% | 42.0% | 14.8% | 92.1 | 4.42 | 5.37 | 4.51 | 4.58 | 1.9 |