| 1 | Max Scherzer | - - - | 85 | 35 | 0 | 167 | 167 | 1068.2 | 11.98 | 2.14 | 1.07 | .272 | 81.1% | 35.2% | 11.3% | 94.7 | 2.75 | | 2.90 | 3.20 | 33.2 |
| 2 | Jacob deGrom | NYM | 54 | 39 | 0 | 146 | 146 | 930.1 | 11.18 | 2.07 | 0.82 | .288 | 80.3% | 45.1% | 11.3% | 96.6 | 2.46 | | 2.62 | 2.88 | 30.5 |
| 3 | Gerrit Cole | - - - | 77 | 43 | 0 | 161 | 161 | 986.0 | 11.25 | 2.38 | 1.13 | .297 | 77.3% | 41.9% | 13.6% | 96.8 | 3.26 | | 3.17 | 3.20 | 25.9 |
| 4 | Chris Sale | - - - | 57 | 34 | 0 | 125 | 125 | 789.0 | 11.95 | 1.95 | 1.05 | .296 | 76.5% | 41.7% | 13.1% | 94.4 | 3.16 | | 2.89 | 2.94 | 23.5 |
| 5 | Aaron Nola | PHI | 61 | 47 | 0 | 158 | 158 | 945.2 | 10.25 | 2.65 | 1.02 | .295 | 73.5% | 48.8% | 13.8% | 92.9 | 3.68 | | 3.37 | 3.36 | 22.6 |
| 6 | Justin Verlander | - - - | 69 | 32 | 0 | 136 | 136 | 876.2 | 10.98 | 2.15 | 1.26 | .254 | 82.9% | 33.3% | 12.4% | 94.8 | 2.87 | | 3.36 | 3.53 | 22.5 |
| 7 | Clayton Kershaw | LAD | 71 | 28 | 0 | 135 | 134 | 843.2 | 9.86 | 1.49 | 1.06 | .266 | 80.9% | 48.6% | 14.5% | 91.8 | 2.60 | | 3.04 | 2.97 | 22.4 |
| 8 | Corey Kluber | - - - | 63 | 26 | 0 | 118 | 118 | 750.1 | 10.02 | 2.11 | 0.96 | .281 | 76.4% | 44.0% | 11.9% | 92.6 | 3.02 | | 3.12 | 3.28 | 19.6 |
| 9 | Trevor Bauer | - - - | 65 | 45 | 1 | 157 | 148 | 935.1 | 10.34 | 3.11 | 1.12 | .289 | 76.0% | 42.5% | 13.1% | 94.3 | 3.52 | | 3.68 | 3.77 | 18.8 |
| 10 | Zack Greinke | - - - | 77 | 39 | 0 | 166 | 165 | 1015.1 | 8.17 | 1.81 | 1.18 | .280 | 75.2% | 45.2% | 13.7% | 90.1 | 3.55 | | 3.70 | 3.70 | 18.7 |
| 11 | Zack Wheeler | - - - | 44 | 34 | 0 | 120 | 120 | 748.1 | 9.08 | 2.49 | 0.84 | .299 | 73.7% | 47.0% | 11.0% | 96.7 | 3.51 | | 3.32 | 3.66 | 18.2 |
| 12 | Stephen Strasburg | WSN | 59 | 24 | 0 | 114 | 114 | 688.2 | 10.68 | 2.61 | 0.98 | .284 | 75.6% | 45.4% | 12.9% | 95.1 | 3.35 | | 3.21 | 3.30 | 17.9 |
| 13 | Charlie Morton | - - - | 62 | 25 | 0 | 134 | 134 | 749.1 | 10.58 | 2.97 | 0.82 | .291 | 74.3% | 48.6% | 12.2% | 95.4 | 3.36 | | 3.24 | 3.41 | 17.8 |
| 14 | Kyle Hendricks | CHC | 68 | 46 | 0 | 162 | 161 | 968.0 | 7.43 | 1.97 | 1.06 | .279 | 76.8% | 45.9% | 12.4% | 87.5 | 3.33 | | 3.84 | 4.00 | 17.2 |
| 15 | Lance Lynn | - - - | 54 | 38 | 0 | 138 | 136 | 792.1 | 9.37 | 3.21 | 1.06 | .287 | 76.0% | 42.3% | 11.7% | 93.9 | 3.60 | | 3.82 | 4.13 | 16.4 |
| 16 | Kevin Gausman | - - - | 50 | 53 | 0 | 171 | 155 | 904.0 | 9.17 | 2.65 | 1.25 | .309 | 75.6% | 42.9% | 14.0% | 94.7 | 3.96 | | 3.91 | 3.85 | 16.0 |
| 17 | German Marquez | COL | 54 | 41 | 0 | 141 | 138 | 814.1 | 9.02 | 2.61 | 1.18 | .307 | 71.1% | 48.7% | 16.1% | 95.3 | 4.28 | | 3.85 | 3.62 | 15.9 |
| 18 | Noah Syndergaard | NYM | 38 | 24 | 0 | 97 | 96 | 568.0 | 9.68 | 2.14 | 0.71 | .323 | 73.0% | 49.6% | 10.1% | 98.2 | 3.34 | | 2.85 | 3.24 | 15.9 |
| 19 | Patrick Corbin | - - - | 55 | 63 | 1 | 177 | 164 | 984.2 | 9.10 | 2.95 | 1.24 | .313 | 72.4% | 49.4% | 16.3% | 92.0 | 4.22 | | 3.99 | 3.71 | 15.6 |
| 20 | James Paxton | - - - | 45 | 25 | 0 | 107 | 107 | 589.2 | 10.61 | 2.53 | 1.04 | .316 | 72.6% | 42.2% | 11.8% | 96.0 | 3.71 | | 3.20 | 3.45 | 15.5 |
| 21 | Carlos Carrasco | - - - | 56 | 40 | 1 | 136 | 123 | 740.0 | 10.16 | 2.24 | 1.23 | .309 | 75.7% | 45.5% | 15.4% | 94.2 | 3.70 | | 3.52 | 3.31 | 15.4 |
| 22 | Marcus Stroman | - - - | 46 | 54 | 0 | 149 | 149 | 870.2 | 7.48 | 2.63 | 0.89 | .306 | 72.6% | 57.7% | 14.7% | 93.6 | 3.69 | | 3.73 | 3.66 | 15.3 |
| 23 | Yu Darvish | - - - | 40 | 42 | 0 | 129 | 129 | 748.0 | 10.96 | 2.70 | 1.35 | .280 | 75.6% | 41.0% | 15.7% | 94.5 | 3.78 | | 3.72 | 3.50 | 15.2 |
| 24 | Jon Gray | COL | 53 | 47 | 0 | 143 | 142 | 788.2 | 9.23 | 3.04 | 1.15 | .313 | 69.7% | 46.9% | 14.8% | 95.5 | 4.54 | | 3.93 | 3.79 | 14.9 |
| 25 | Jose Berrios | - - - | 60 | 47 | 0 | 148 | 147 | 851.2 | 9.06 | 2.81 | 1.14 | .290 | 72.1% | 41.1% | 12.2% | 93.8 | 4.04 | | 3.95 | 4.18 | 14.9 |
| 26 | Jose Quintana | - - - | 50 | 46 | 0 | 161 | 138 | 815.0 | 8.78 | 2.90 | 1.14 | .307 | 72.3% | 43.3% | 12.8% | 92.1 | 4.17 | | 3.90 | 3.99 | 14.5 |
| 27 | Luis Castillo | CIN | 40 | 49 | 0 | 123 | 123 | 707.1 | 9.80 | 3.30 | 1.08 | .287 | 73.5% | 53.9% | 16.7% | 96.7 | 3.72 | | 3.76 | 3.50 | 14.5 |
| 28 | Walker Buehler | LAD | 40 | 13 | 0 | 103 | 94 | 573.1 | 9.92 | 2.28 | 0.94 | .261 | 76.0% | 45.1% | 11.9% | 96.2 | 2.90 | | 3.20 | 3.45 | 14.2 |
| 29 | Shane Bieber | CLE | 41 | 18 | 0 | 82 | 80 | 503.0 | 11.33 | 2.09 | 1.11 | .314 | 77.5% | 45.2% | 14.7% | 93.3 | 3.29 | | 3.05 | 3.00 | 13.9 |
| 30 | Sonny Gray | - - - | 49 | 52 | 0 | 147 | 140 | 776.1 | 9.30 | 3.48 | 1.05 | .289 | 71.2% | 51.1% | 14.9% | 93.4 | 4.07 | | 3.91 | 3.79 | 13.8 |