| 1 | Mike Foltynewicz | 13 | 10 | 0 | 31 | 31 | 183.0 | 9.93 | 3.34 | 0.84 | .251 | 77.1% | 43.1% | 9.6% | 96.4 | 2.85 | 3.13 | 3.37 | 3.77 | 3.8 |
| 2 | Anibal Sanchez | 7 | 6 | 0 | 24 | 24 | 133.2 | 8.96 | 2.63 | 1.01 | .258 | 78.7% | 45.5% | 11.4% | 90.7 | 2.90 | | 3.59 | 3.77 | 2.5 |
| 3 | Sean Newcomb | 12 | 9 | 0 | 30 | 30 | 163.1 | 8.76 | 4.41 | 0.99 | .274 | 74.7% | 43.5% | 11.2% | 93.0 | 3.91 | | 4.13 | 4.33 | 1.9 |
| 4 | Kevin Gausman | 5 | 3 | 0 | 10 | 10 | 59.2 | 6.64 | 2.72 | 0.75 | .260 | 74.6% | 43.8% | 7.8% | 93.6 | 2.87 | | 3.78 | 4.46 | 0.9 |
| 5 | Julio Teheran | 9 | 9 | 0 | 31 | 31 | 175.2 | 8.30 | 4.30 | 1.33 | .217 | 75.6% | 38.0% | 13.5% | 90.0 | 3.94 | 4.48 | 4.83 | 4.72 | 0.7 |
| 6 | Mike Soroka | 2 | 1 | 0 | 5 | 5 | 25.2 | 7.36 | 2.45 | 0.35 | .345 | 64.6% | 44.0% | 5.0% | 92.5 | 3.51 | 4.67 | 2.85 | 3.63 | 0.6 |
| 7 | Max Fried | 1 | 2 | 0 | 5 | 5 | 21.2 | 11.22 | 5.82 | 0.00 | .319 | 77.4% | 52.2% | 0.0% | 92.8 | 2.49 | | 2.88 | 3.42 | 0.5 |
| 8 | Touki Toussaint | 2 | 1 | 0 | 5 | 5 | 27.0 | 9.67 | 5.67 | 0.33 | .242 | 74.4% | 49.2% | 6.7% | 93.5 | 3.33 | | 3.60 | 4.04 | 0.5 |
| 9 | Matt Wisler | 1 | 1 | 0 | 3 | 3 | 17.1 | 6.75 | 2.60 | 1.04 | .280 | 76.9% | 26.9% | 8.3% | 92.4 | 3.63 | | 4.03 | 4.81 | 0.2 |
| 10 | Brandon McCarthy | 6 | 3 | 0 | 15 | 15 | 78.2 | 7.44 | 2.40 | 1.72 | .332 | 74.5% | 48.0% | 21.7% | 91.6 | 4.92 | 4.76 | 4.79 | 3.76 | 0.2 |
| 11 | Bryse Wilson | 1 | 0 | 0 | 1 | 1 | 5.0 | 9.00 | 5.40 | 0.00 | .273 | 100.0% | 54.5% | 0.0% | 94.9 | 0.00 | | 2.96 | 3.95 | 0.1 |
| 12 | Luiz Gohara | 0 | 1 | 0 | 1 | 1 | 4.0 | 13.50 | 9.00 | 0.00 | .400 | 75.0% | 44.4% | 0.0% | 94.7 | 4.50 | | 3.16 | 4.81 | 0.1 |
| 13 | Kolby Allard | 1 | 0 | 0 | 1 | 1 | 5.0 | 1.80 | 3.60 | 1.80 | .381 | 66.0% | 42.9% | 16.7% | 89.2 | 7.20 | | 7.16 | 6.54 | -0.1 |