| 1 | Max Scherzer | 18 | 7 | 0 | 33 | 33 | 220.2 | 12.24 | 2.08 | 0.94 | .265 | 81.3% | 34.3% | 9.7% | 94.5 | 2.53 | 2.56 | 2.65 | 3.06 | 7.5 |
| 2 | Stephen Strasburg | 10 | 7 | 0 | 22 | 22 | 130.0 | 10.80 | 2.63 | 1.25 | .309 | 75.6% | 43.6% | 15.7% | 94.8 | 3.74 | 3.95 | 3.62 | 3.28 | 2.4 |
| 3 | Tanner Roark | 9 | 14 | 0 | 30 | 30 | 180.0 | 7.30 | 2.50 | 1.15 | .295 | 73.0% | 40.8% | 11.3% | 91.6 | 4.25 | | 4.20 | 4.41 | 2.4 |
| 4 | Gio Gonzalez | 7 | 11 | 0 | 27 | 27 | 145.2 | 7.78 | 4.32 | 0.93 | .319 | 72.5% | 45.5% | 11.1% | 90.3 | 4.57 | | 4.25 | 4.44 | 1.7 |
| 5 | Jeremy Hellickson | 5 | 3 | 0 | 19 | 19 | 91.1 | 6.41 | 1.97 | 1.08 | .252 | 71.7% | 45.9% | 12.4% | 89.8 | 3.45 | 4.33 | 4.22 | 4.27 | 1.3 |
| 6 | Tommy Milone | 1 | 1 | 0 | 4 | 4 | 22.1 | 8.06 | 0.40 | 1.61 | .375 | 73.0% | 30.1% | 12.1% | 87.4 | 5.24 | | 3.97 | 4.08 | 0.4 |
| 7 | Erick Fedde | 2 | 4 | 0 | 11 | 11 | 50.1 | 8.23 | 3.93 | 1.43 | .333 | 69.9% | 53.1% | 22.2% | 93.6 | 5.54 | 5.81 | 4.71 | 3.83 | 0.3 |
| 8 | Austin Voth | 1 | 1 | 0 | 2 | 2 | 9.1 | 7.71 | 4.82 | 0.96 | .310 | 58.8% | 50.0% | 9.1% | 91.3 | 6.75 | | 4.45 | 5.00 | 0.1 |
| 9 | Kyle McGowin | 0 | 0 | 0 | 1 | 1 | 4.0 | 9.00 | 6.75 | 0.00 | .111 | 100.0% | 44.4% | 0.0% | 91.3 | 0.00 | | 3.41 | 5.06 | 0.1 |
| 10 | Joe Ross | 0 | 2 | 0 | 3 | 3 | 16.0 | 3.94 | 2.25 | 1.69 | .269 | 69.1% | 36.4% | 13.0% | 93.3 | 5.06 | 4.73 | 5.85 | 5.78 | -0.1 |
| 11 | A.J. Cole | 0 | 1 | 0 | 2 | 2 | 9.0 | 9.00 | 5.00 | 4.00 | .333 | 48.4% | 17.2% | 22.2% | 92.3 | 12.00 | | 8.60 | 6.13 | -0.3 |
| 12 | Jefry Rodriguez | 2 | 2 | 0 | 8 | 8 | 38.2 | 7.22 | 6.52 | 1.63 | .266 | 62.9% | 42.0% | 16.3% | 95.6 | 6.75 | | 6.32 | 5.80 | -0.3 |