| 1 | Trevor Bauer | 12 | 6 | 0 | 27 | 27 | 171.1 | 11.50 | 2.99 | 0.47 | .301 | 79.3% | 44.1% | 6.3% | 94.6 | 2.26 | | 2.44 | 3.14 | 5.7 |
| 2 | Corey Kluber | 20 | 7 | 0 | 33 | 33 | 215.0 | 9.29 | 1.42 | 1.05 | .276 | 77.9% | 44.4% | 13.1% | 92.1 | 2.89 | 3.20 | 3.12 | 3.08 | 5.5 |
| 3 | Carlos Carrasco | 16 | 9 | 0 | 30 | 30 | 186.2 | 10.66 | 1.88 | 1.01 | .314 | 75.3% | 46.5% | 13.2% | 93.8 | 3.33 | | 2.98 | 2.92 | 5.0 |
| 4 | Mike Clevinger | 13 | 8 | 0 | 32 | 32 | 200.0 | 9.31 | 3.01 | 0.94 | .280 | 79.8% | 40.5% | 10.2% | 93.8 | 3.01 | 3.35 | 3.52 | 3.86 | 4.2 |
| 5 | Shane Bieber | 11 | 4 | 0 | 19 | 19 | 110.0 | 9.57 | 1.72 | 0.90 | .356 | 70.2% | 45.3% | 10.6% | 93.2 | 4.25 | | 2.96 | 3.22 | 2.9 |
| 6 | Adam Plutko | 4 | 5 | 0 | 12 | 12 | 68.0 | 7.01 | 2.65 | 2.25 | .255 | 74.8% | 26.7% | 14.0% | 91.0 | 5.29 | | 5.78 | 5.47 | -0.1 |
| 7 | Josh Tomlin | 0 | 3 | 0 | 9 | 9 | 42.2 | 5.70 | 1.27 | 3.80 | .296 | 78.1% | 28.3% | 22.8% | 87.4 | 7.17 | | 8.08 | 5.66 | -1.0 |