| 1 | Adrian Houser | MIL | .213 | 2.39 | 20.3% | 56.2% | 23.5% | 13.9% | 2.8% | 43 | 7.21 | 332 | 518 | 850 | 35.9% | 44.2% | 19.9% | 23.1% | 58.3% | 18.6% |
| 2 | Alek Manoah | TOR | .253 | 1.01 | 24.6% | 38.0% | 37.4% | 11.9% | 7.5% | 54 | 6.81 | 417 | 720 | 1137 | 36.3% | 34.6% | 29.1% | 20.7% | 57.0% | 22.3% |
| 3 | Zack Wheeler | PHI | .288 | 1.88 | 23.4% | 50.0% | 26.6% | 13.6% | 13.6% | 43 | 4.13 | 448 | 951 | 1399 | 39.7% | 34.1% | 26.2% | 23.0% | 54.4% | 22.6% |
| 4 | Chris Sale | BOS | .358 | 1.50 | 21.1% | 47.4% | 31.6% | 5.6% | 16.7% | 50 | 10.55 | 249 | 487 | 736 | 43.5% | 33.9% | 22.6% | 22.6% | 53.9% | 23.5% |
| 5 | Corbin Burnes | MIL | .297 | 1.63 | 22.8% | 47.8% | 29.3% | 5.6% | 7.4% | 48 | 5.45 | 417 | 816 | 1233 | 43.5% | 36.6% | 19.9% | 19.9% | 56.5% | 23.7% |
| 6 | Tyler Mahle | CIN | .305 | 1.08 | 22.9% | 40.1% | 37.0% | 11.9% | 14.3% | 51 | 5.42 | 556 | 946 | 1502 | 39.6% | 37.4% | 23.0% | 17.0% | 59.1% | 23.8% |
| 7 | Ryan Yarbrough | TBR | .306 | 0.69 | 27.0% | 29.8% | 43.3% | 11.5% | 13.1% | 27 | 5.98 | 205 | 459 | 664 | 36.6% | 34.5% | 28.9% | 21.1% | 54.9% | 23.9% |
| 8 | Julio Urias | LAD | .258 | 0.92 | 15.7% | 40.3% | 44.0% | 10.5% | 4.2% | 58 | 6.58 | 377 | 830 | 1207 | 33.9% | 41.2% | 24.9% | 22.6% | 53.4% | 24.0% |
| 9 | Tyler Anderson | - - - | .306 | 0.71 | 21.8% | 32.4% | 45.8% | 13.6% | 10.7% | 28 | 3.62 | 325 | 774 | 1099 | 42.2% | 33.0% | 24.8% | 18.7% | 56.1% | 25.2% |
| 10 | Logan Webb | SFG | .304 | 3.25 | 18.7% | 62.2% | 19.1% | 2.1% | 10.4% | 63 | 5.89 | 464 | 923 | 1387 | 39.2% | 34.9% | 25.9% | 16.9% | 57.6% | 25.5% |
| 11 | Max Fried | ATL | .237 | 2.23 | 16.3% | 57.7% | 25.9% | 9.7% | 9.7% | 60 | 5.81 | 458 | 895 | 1353 | 37.2% | 38.1% | 24.7% | 19.0% | 54.3% | 26.7% |
| 12 | Cal Quantrill | CLE | .240 | 1.29 | 17.4% | 46.6% | 36.0% | 9.4% | 10.6% | 53 | 5.42 | 506 | 840 | 1346 | 37.4% | 36.6% | 26.1% | 22.3% | 50.8% | 26.9% |
| 13 | Marco Gonzales | SEA | .203 | 0.66 | 15.9% | 33.3% | 50.8% | 15.6% | 10.9% | 49 | 5.09 | 466 | 897 | 1363 | 36.9% | 33.7% | 29.4% | 22.4% | 50.6% | 27.1% |
| 14 | Carlos Rodon | CHW | .248 | 0.67 | 14.3% | 34.3% | 51.4% | 11.1% | 11.1% | 33 | 6.91 | 244 | 464 | 708 | 31.8% | 42.1% | 26.2% | 21.5% | 51.4% | 27.1% |
| 15 | Keegan Akin | BAL | .288 | 0.78 | 17.9% | 35.9% | 46.2% | 11.9% | 11.9% | 19 | 3.69 | 305 | 553 | 858 | 38.1% | 28.6% | 33.3% | 15.0% | 57.8% | 27.2% |
| 16 | Nestor Cortes | NYY | .265 | 0.45 | 19.8% | 24.9% | 55.4% | 13.3% | 13.3% | 29 | 3.99 | 373 | 693 | 1066 | 32.4% | 39.1% | 28.5% | 17.3% | 55.3% | 27.4% |
| 17 | Steven Matz | TOR | .306 | 1.44 | 21.6% | 46.3% | 32.2% | 13.7% | 8.2% | 70 | 8.48 | 442 | 817 | 1259 | 30.7% | 36.0% | 33.3% | 18.0% | 54.4% | 27.6% |
| 18 | Brandon Woodruff | MIL | .323 | 0.95 | 31.2% | 33.5% | 35.3% | 0.0% | 15.0% | 23 | 3.14 | 344 | 771 | 1115 | 36.4% | 42.8% | 20.8% | 15.6% | 56.6% | 27.7% |
| 19 | Mike Minor | KCR | .261 | 0.91 | 19.5% | 38.4% | 42.1% | 6.0% | 13.4% | 24 | 4.13 | 285 | 555 | 840 | 49.4% | 26.5% | 24.1% | 17.3% | 54.9% | 27.8% |
| 20 | Lance McCullers Jr. | HOU | .284 | 2.68 | 17.2% | 60.3% | 22.5% | 2.1% | 14.9% | 57 | 6.21 | 538 | 888 | 1426 | 44.1% | 29.4% | 26.5% | 11.4% | 60.7% | 28.0% |
| 21 | Nathan Eovaldi | BOS | .314 | 0.96 | 19.1% | 39.5% | 41.4% | 13.5% | 11.2% | 43 | 4.90 | 388 | 886 | 1274 | 33.2% | 37.8% | 29.0% | 17.5% | 54.4% | 28.1% |
| 22 | Charlie Morton | ATL | .259 | 1.55 | 20.2% | 48.6% | 31.3% | 12.3% | 10.8% | 61 | 6.33 | 479 | 886 | 1365 | 39.2% | 34.4% | 26.4% | 20.3% | 51.4% | 28.3% |
| 23 | Wade Miley | CIN | .332 | 1.52 | 26.1% | 44.5% | 29.4% | 12.9% | 17.7% | 52 | 7.02 | 408 | 686 | 1094 | 43.4% | 32.0% | 24.7% | 16.0% | 55.7% | 28.3% |
| 24 | Lucas Giolito | CHW | .247 | 0.73 | 23.2% | 32.3% | 44.4% | 11.4% | 10.2% | 47 | 5.67 | 429 | 759 | 1188 | 40.7% | 35.2% | 24.1% | 17.1% | 54.3% | 28.6% |
| 25 | J.A. Happ | - - - | .309 | 0.84 | 21.2% | 35.8% | 42.9% | 4.1% | 13.4% | 43 | 5.53 | 445 | 731 | 1176 | 34.3% | 40.0% | 25.7% | 13.9% | 57.4% | 28.7% |
| 26 | Ranger Suarez | PHI | .295 | 2.11 | 16.4% | 56.7% | 26.9% | 6.5% | 2.2% | 24 | 3.29 | 376 | 641 | 1017 | 36.8% | 40.2% | 23.0% | 14.4% | 56.9% | 28.7% |
| 27 | Walker Buehler | LAD | .267 | 1.56 | 21.0% | 48.1% | 30.9% | 16.0% | 8.0% | 45 | 4.34 | 462 | 938 | 1400 | 42.3% | 34.1% | 23.6% | 19.9% | 51.2% | 28.9% |
| 28 | Lance Lynn | CHW | .287 | 1.05 | 16.9% | 42.6% | 40.4% | 10.8% | 12.2% | 25 | 3.39 | 391 | 713 | 1104 | 39.0% | 29.4% | 31.6% | 16.6% | 54.5% | 28.9% |
| 29 | Jon Lester | - - - | .268 | 1.41 | 23.9% | 44.5% | 31.6% | 6.4% | 16.7% | 48 | 5.54 | 477 | 735 | 1212 | 41.7% | 39.7% | 18.7% | 16.3% | 54.8% | 29.0% |
| 30 | Kris Bubic | KCR | .277 | 1.69 | 24.7% | 47.3% | 28.0% | 13.5% | 17.3% | 28 | 3.86 | 398 | 673 | 1071 | 39.8% | 38.2% | 22.0% | 17.7% | 53.2% | 29.0% |