ZiPS Projections Courtesy of Dan Szymborski
| Zack Wheeler | PHI | 30 | 30 | 186.0 | 14 | 8 | | | 165 | 67 | 14 | 199 | 43 | 1.12 | 9.66 | 2.09 | 3.23 | 2.74 | 5.2 | 4.5 |
| Gerrit Cole | NYY | 32 | 32 | 188.0 | 16 | 6 | | | 149 | 63 | 22 | 245 | 47 | 1.04 | 11.72 | 2.24 | 3.04 | 2.81 | 5.1 | 4.0 |
| Kevin Gausman | TOR | 30 | 30 | 176.0 | 12 | 8 | | | 159 | 60 | 15 | 193 | 29 | 1.07 | 9.87 | 1.50 | 3.06 | 2.58 | 5.0 | 4.1 |
| Dylan Cease | CHW | 32 | 32 | 166.0 | 13 | 7 | | | 135 | 65 | 17 | 226 | 73 | 1.25 | 12.27 | 3.94 | 3.55 | 3.14 | 3.9 | 2.4 |
| Corbin Burnes | MIL | 28 | 28 | 171.0 | 9 | 5 | | | 127 | 52 | 20 | 217 | 42 | 0.99 | 11.45 | 2.19 | 2.76 | 2.97 | 3.9 | 5.3 |
| Max Scherzer | NYM | 29 | 29 | 174.0 | 15 | 6 | | | 132 | 57 | 22 | 226 | 42 | 1.00 | 11.68 | 2.18 | 2.94 | 3.05 | 3.9 | 4.3 |
| Walker Buehler | LAD | 32 | 32 | 188.0 | 15 | 5 | | | 162 | 66 | 19 | 186 | 47 | 1.11 | 8.93 | 2.23 | 3.17 | 3.28 | 3.8 | 4.3 |
| Freddy Peralta | MIL | 27 | 33 | 146.0 | 11 | 6 | | | 111 | 60 | 13 | 196 | 57 | 1.15 | 12.11 | 3.51 | 3.69 | 2.91 | 3.8 | 2.6 |
| Max Fried | ATL | 28 | 28 | 170.0 | 15 | 7 | | | 152 | 61 | 15 | 164 | 32 | 1.09 | 8.68 | 1.72 | 3.24 | 3.04 | 3.7 | 4.2 |
| Carlos Rodón | SFG | 25 | 25 | 135.0 | 13 | 7 | | | 108 | 50 | 10 | 178 | 49 | 1.16 | 11.86 | 3.29 | 3.31 | 2.69 | 3.6 | 2.8 |
| Justin Verlander | HOU | 26 | 26 | 163.0 | 16 | 5 | | | 114 | 47 | 22 | 182 | 31 | 0.89 | 10.04 | 1.71 | 2.61 | 3.31 | 3.6 | 4.5 |
| Joe Musgrove | SDP | 30 | 31 | 181.0 | 14 | 6 | | | 153 | 61 | 20 | 193 | 42 | 1.07 | 9.55 | 2.07 | 3.01 | 3.25 | 3.5 | 4.5 |
| Shane Bieber | CLE | 27 | 27 | 158.0 | 9 | 7 | | | 141 | 59 | 17 | 186 | 42 | 1.16 | 10.58 | 2.41 | 3.34 | 3.04 | 3.5 | 2.8 |
| Aaron Nola | PHI | 33 | 33 | 190.0 | 10 | 9 | | | 159 | 78 | 28 | 228 | 46 | 1.08 | 10.80 | 2.19 | 3.68 | 3.52 | 3.5 | 3.4 |
| Sandy Alcantara | MIA | 34 | 34 | 209.0 | 14 | 9 | | | 174 | 73 | 17 | 196 | 69 | 1.16 | 8.41 | 2.98 | 3.14 | 3.47 | 3.3 | 4.8 |
| Logan Webb | SFG | 28 | 29 | 160.0 | 13 | 5 | | | 151 | 58 | 9 | 144 | 42 | 1.21 | 8.08 | 2.38 | 3.29 | 2.98 | 3.2 | 3.5 |
| Brandon Woodruff | MIL | 28 | 29 | 156.0 | 14 | 7 | | | 134 | 63 | 19 | 188 | 42 | 1.13 | 10.83 | 2.44 | 3.65 | 3.21 | 3.1 | 2.9 |
| Shohei Ohtani | LAA | 23 | 23 | 124.0 | 8 | 5 | | | 100 | 45 | 12 | 158 | 39 | 1.12 | 11.45 | 2.82 | 3.25 | 2.93 | 3.1 | 2.3 |
| Tarik Skubal | DET | 30 | 31 | 159.0 | 11 | 9 | | | 145 | 61 | 19 | 174 | 43 | 1.18 | 9.87 | 2.42 | 3.45 | 3.33 | 3.1 | 2.6 |
| Pablo López | MIA | 26 | 26 | 138.0 | 10 | 5 | | | 115 | 44 | 11 | 142 | 34 | 1.08 | 9.27 | 2.21 | 2.85 | 2.95 | 3.1 | 3.7 |
| Lucas Giolito | CHW | 28 | 28 | 156.0 | 11 | 7 | | | 126 | 58 | 23 | 201 | 51 | 1.13 | 11.60 | 2.93 | 3.36 | 3.49 | 3.1 | 2.7 |
| Tyler Mahle | CIN | 33 | 33 | 168.0 | 10 | 11 | | | 155 | 82 | 19 | 183 | 68 | 1.33 | 9.80 | 3.63 | 4.39 | 3.69 | 3.0 | 1.9 |
| Frankie Montas | OAK | 31 | 31 | 175.0 | 11 | 10 | | | 151 | 70 | 22 | 192 | 49 | 1.14 | 9.88 | 2.52 | 3.57 | 3.47 | 2.9 | 2.1 |
| Clayton Kershaw | LAD | 22 | 22 | 125.0 | 13 | 4 | | | 100 | 40 | 16 | 139 | 21 | 0.97 | 9.99 | 1.54 | 2.91 | 3.08 | 2.9 | 3.3 |
| Alek Manoah | TOR | 26 | 26 | 146.0 | 12 | 5 | | | 114 | 46 | 13 | 150 | 41 | 1.06 | 9.24 | 2.50 | 2.81 | 3.38 | 2.7 | 3.8 |
| Eduardo Rodriguez | DET | 30 | 31 | 157.0 | 9 | 10 | | | 147 | 67 | 17 | 158 | 56 | 1.29 | 9.05 | 3.19 | 3.85 | 3.57 | 2.6 | 1.7 |
| Jameson Taillon | NYY | 28 | 28 | 144.0 | 10 | 6 | | | 142 | 61 | 18 | 129 | 30 | 1.20 | 8.08 | 1.90 | 3.79 | 3.72 | 2.5 | 1.6 |
| Julio Urías | LAD | 30 | 32 | 164.0 | 13 | 8 | | | 145 | 60 | 23 | 154 | 35 | 1.10 | 8.44 | 1.92 | 3.31 | 3.78 | 2.4 | 3.5 |
| Robbie Ray | SEA | 30 | 30 | 181.0 | 12 | 10 | | | 146 | 80 | 28 | 218 | 60 | 1.14 | 10.84 | 3.00 | 3.96 | 3.81 | 2.4 | 1.2 |
| Michael Kopech | CHW | 17 | 33 | 107.0 | 5 | 3 | | | 71 | 32 | 6 | 122 | 50 | 1.13 | 10.23 | 4.23 | 2.68 | 3.12 | 2.4 | 2.6 |